958255-23-7

Basic information

• Product Name: {3-[4-(2-amino-ethyl)-2,6-dibromo-phenoxy]-propyl}-methyl-carbamic acid methyl ester
• Synonyms: {3-[4-(2-amino-ethyl)-2,6-dibromo-phenoxy]-propyl}-methyl-carbamic acid methyl ester
• CAS NO: 958255-23-7
• Molecular Weight: 424.132
• Mol File: 958255-23-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {3-[4-(2-amino-ethyl)-2,6-dibromo-phenoxy]-propyl}-methyl-carbamic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {3-[4-(2-amino-ethyl)-2,6-dibromo-phenoxy]-propyl}-methyl-carbamic acid methyl ester(958255-23-7)
• EPA Substance Registry System: {3-[4-(2-amino-ethyl)-2,6-dibromo-phenoxy]-propyl}-methyl-carbamic acid methyl ester(958255-23-7)

Safety Data

• Hazardous Substances Data: 958255-23-7(Hazardous Substances Data)

Upstream product

• 210880-88-9 N-(tert-butoxycarbonyl)-3,5-dibromo-4-hydroxy-β-phenethylamine 
• 212688-02-3 3,5-dibromo-4-hydroxyphenylacetic acid methyl ester 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 958255-21-5 {2-[3,5-dibromo-4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-ethyl}-carbamic acid tert-butyl ester 
• 958255-27-1 methanesulfonic acid 2-[3,5-dibromo-4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-ethyl ester 
• 958255-18-0 3,5-dibromo-4-{[tert-butyl(dimethyl)silyl]oxy}phenylacetic acid methyl ester 
• 958255-20-4 [4-(2-azido-ethyl)-2,6-dibromo-phenoxy]-tert-butyl-dimethyl-silane 
• 958255-19-1 2-[3,5-dibromo-4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-ethanol 
• 958255-17-9 methyl (3-hydroxypropyl)(methyl)carbamate 
• 954100-52-8 methyl (3-bromopropyl)methylcarbamate 
• 958255-22-6 {3-[2,6-dibromo-4-(2-tert-butoxycarbonylamino-ethyl)-phenoxy]-propyl}-methyl-carbamic acid methyl ester 

Relevant articles and documents

Total synthesis of antibacterial dibromotyrosine derived alkaloid purpuramine-K#

The first total synthesis of a dibromotyrosine derived alkaloid purpuramine K 1 reported for possible anti-bacterial activity against gram-positive bacteria viz: Staphylococcus aureus, Bacillus subtilis, Bacillus sphaericus and gram-negative bacteria like Chromobacterium violaceum, Klebsiella aerogenes, and Pseudomonas aeruginosa has been achieved. The synthesis involves preparation of methyl-3-bromopropyl carbamate 6, and Boc protected 2-[3,5-dibromo, 4-hydroxy phenyl] ethyl amine 13 which is followed by coupling of these two structural fragments to give corresponding ether 14. After deprotection of Boc group in compound 14, it is reacted with 4-hydroxyphenyl pyruvic acid oxime derivative 17 using EDCI/HOBT to give compound 18, which is further transformed to purpuramine K.