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METHYL-3,5-DIBROMO-4-HYDROXYPHENYLACETATE is a chemical compound that belongs to the class of phenylacetates. It is a methyl ester derivative of 3,5-dibromo-4-hydroxyphenylacetic acid, which is a brominated derivative of phenylacetic acid. METHYL-3,5-DIBROMO-4-HYDROXYPHENYLACETATE possesses unique chemical properties, making it a versatile intermediate in various synthesis processes.

212688-02-3

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212688-02-3 Usage

Uses

Used in Pharmaceutical Industry:
METHYL-3,5-DIBROMO-4-HYDROXYPHENYLACETATE is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into the molecular structures of various drugs. Its unique chemical properties allow for the development of new therapeutic agents with potential applications in treating different medical conditions.
Used in Agrochemical Industry:
In the agrochemical industry, METHYL-3,5-DIBROMO-4-HYDROXYPHENYLACETATE serves as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its chemical properties contribute to the development of effective products for agricultural use, helping to protect crops and enhance yield.
Used in Antimicrobial Applications:
METHYL-3,5-DIBROMO-4-HYDROXYPHENYLACETATE has been studied for its potential antimicrobial properties, making it a candidate for use in various applications where inhibition of microbial growth is required. This can include uses in healthcare, food preservation, and water treatment.
Used in Antioxidant Applications:
METHYL-3,5-DIBROMO-4-HYDROXYPHENYLACETATE has also been investigated for its antioxidant properties, which can be beneficial in various industries, such as cosmetics, food and beverage, and pharmaceuticals. Its ability to neutralize free radicals can help prevent oxidation and extend the shelf life of products, as well as provide health benefits in certain applications.

Check Digit Verification of cas no

The CAS Registry Mumber 212688-02-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,2,6,8 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 212688-02:
(8*2)+(7*1)+(6*2)+(5*6)+(4*8)+(3*8)+(2*0)+(1*2)=123
123 % 10 = 3
So 212688-02-3 is a valid CAS Registry Number.

212688-02-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(3,5-dibromo-4-hydroxyphenyl)propanoate

1.2 Other means of identification

Product number -
Other names METHYL-3,5-DIBROMO-4-HYDROXYPHENYLACETATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:212688-02-3 SDS

212688-02-3Relevant academic research and scientific papers

Synthesis of (+)-O-methylthalibrine by employing a stereocontrolled Bischler-Napieralski reaction and an electrochemically generated diaryl ether

Kawabata, Yuki,Naito, Yu,Saitoh, Tsuyoshi,Kawa, Kohei,Fuchigami, Toshio,Nishiyama, Shigeru

, p. 99 - 104 (2014/01/06)

An efficient electrochemical four-step route was developed for the preparation of diaryl ether derivatives by using halogenation and dehalogenation processes in addition to electrochemical phenolic oxidation and reduction reactions. The synthesis of (+)-O

Electrochemical construction of the diaryl ethers: A synthetic approach to o-methylthalibrine

Naito, Yu,Tanabe, Takamasa,Kawabata, Yuki,Ishikawa, Yuichi,Nishiyama, Shigeru

body text, p. 4776 - 4778 (2010/09/20)

Electrochemical dimerization of halogenated p-hydroxyphenylacetic acid derivatives followed by Zn reduction provided the corresponding diaryl ethers. Manipulation of the reduction step using several procedures increased its efficiency, which enabled the construction of o-methylthalibrine, an isoquinoline-class alkaloid.

Total synthesis of antibacterial dibromotyrosine derived alkaloid purpuramine-K#

Reddy, S. Malla,Srinivasulu,Venkateswarlu

, p. 2757 - 2762 (2007/10/03)

The first total synthesis of a dibromotyrosine derived alkaloid purpuramine K 1 reported for possible anti-bacterial activity against gram-positive bacteria viz: Staphylococcus aureus, Bacillus subtilis, Bacillus sphaericus and gram-negative bacteria like Chromobacterium violaceum, Klebsiella aerogenes, and Pseudomonas aeruginosa has been achieved. The synthesis involves preparation of methyl-3-bromopropyl carbamate 6, and Boc protected 2-[3,5-dibromo, 4-hydroxy phenyl] ethyl amine 13 which is followed by coupling of these two structural fragments to give corresponding ether 14. After deprotection of Boc group in compound 14, it is reacted with 4-hydroxyphenyl pyruvic acid oxime derivative 17 using EDCI/HOBT to give compound 18, which is further transformed to purpuramine K.

Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta

Hangeland, Jon J.,Doweyko, Arthur M.,Dejneka, Tamara,Friends, Todd J.,Devasthale, Pratik,Mellstroem, Karin,Sandberg, Johnny,Grynfarb, Marlena,Sack, John S.,Einspahr, Howard,Faernegardh, Mathias,Husman, Bolette,Ljunggren, Jan,Koehler, Konrad,Sheppard, Cheryl,Malm, Johan,Ryono, Denis E.

, p. 3549 - 3553 (2007/10/03)

A set of thyromimetics having improved selectivity for TR-β1 were prepared by replacing the 3′-isopropyl group of 2 and 3 with substituents having increased steric bulk. From this limited SAR study, the most potent and selective compounds ident

Thyroid receptor ligands and method

-

, (2008/06/13)

Novel thyroid receptor ligands are provided which have the general formula (I) where R1is alkyl of 1 to 4 carbons or cycloalkyl of 3 to 7 carbons; R2and R3are the same or different and are hydrogen, halogen, alkyl of 1 to

Syntheses of the marine metabolites verongamine, hemibastadin-2, and aerothionin using the cyano ylide coupling methodology

Wasserman, Harry H.,Wang, Jianji

, p. 5581 - 5586 (2007/10/03)

Syntheses of the marine metabolites verongamine, hemibastadin-2, and aerothionin have been accomplished by a methodology involving the conversion of a carboxylic acid to an acyl cyano phosphorane which may be oxidized to an α,β-diketo nitrile. This strong

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