95836-15-0Relevant academic research and scientific papers
Acid-catalyzed solvolysis of polyenol ethers. II. Effect of the degree of unsaturation
Vertegaal,Van Der Gen
, p. 7301 - 7312 (1990)
The acid-catalyzed solvolysis of polyenol ethers of glycerol gradually changes with increasing unsaturation from the regular pattern into an anomalous one in which hydroxy- and methoxy-substituted aldehydes are formed.
A CONVENIENT SYNTHESIS OF FECAPENTAENE-12 BY THE HORNER-WITTIG REACTION
Wit, P. P. de,Schaik, T. A. M. van,Gen, A. van der
, p. 369 - 370 (2007/10/02)
A synthesis of racemic fecapentaene-12 and other glyceryl enol ethers has been developed based on the Horner-Wittig reaction.Coupling of the anion of the glyceryl substituted phosphine oxide 7 with unsaturated aldehydes 9a-c provided, after treatment with base, the silyl protected glyceryl enol ethers 11a-c.The silyl groups were easily removed and mixtures of E and Z isomers of glyceryl enol ethers 12a-c were obtained.The isomers could be separated upon washing with ether/hexane.
