91423-46-0Relevant academic research and scientific papers
Acid-catalyzed solvolysis of polyenol ethers. II. Effect of the degree of unsaturation
Vertegaal,Van Der Gen
, p. 7301 - 7312 (2007/10/02)
The acid-catalyzed solvolysis of polyenol ethers of glycerol gradually changes with increasing unsaturation from the regular pattern into an anomalous one in which hydroxy- and methoxy-substituted aldehydes are formed.
ISOLATION AND STRUCTURE ELUCIDATION OF PLASMALOPENTAENE-12, THE BIOLOGICAL PRECURSOR OF PECAPENTAENE-12.
Kingston, David G. I.,Duh, C.-Y.,Piccariello, T.,Keyes, R. F.,Van Tassel, R. L.,Wilkins, T. D.
, p. 6665 - 6668 (2007/10/02)
The biological precursor of the potent fecal mutagen fecapentaene-12 has been purified and its structure elucidated as the polyunsaturated plasmalogen 2.The occurrence of 2 in germ-free animals indicates that it is a new mammalian product.
SYNTHESIS OF THE E- AND Z-ISOMERS OF THE POTENT MUTAGEN (S)-FECAPENTAENE-12 BY THE HORNER-WITTIG REACTION
Wit, P.P de,van der Steeg, M.,van der Gen, A.
, p. 307 - 308 (2007/10/02)
A synthesis of the E- and Z-isomers of optically pure (S)-fecapentaene-12 is described.The method is beased on the chromatographic separation of diastereomeric adducts, formed as intermediates in the Horner-Wittig reaction of an all-trans undecatetraenal,
Total Synthesis of the Potent Mutagen (S)-3-(Dodeca-1,3,5,7,9-pentaenyloxy)propane-1,2-diol
Nicolaou, K. C.,Zipkin, Robert,Tanner, David
, p. 349 - 350 (2007/10/02)
A total synthesis of the mutagenic (S)-3-(dodeca-1,3,5,7,9-pentaenyloxy)propane-1,2-diol (1) from (R)-glycerol acetonide (2), potassium glutaconate (6), and the diphenylphosphine oxide (11) is reported.
SYNTHESIS OF RACEMIC FECAPENTAENE-12, A POTENT MUTAGEN FROM HUMAN FECES, AND ITS REGIOISOMER
Gunatilaka, A. A. Leslie,Hirai, Nobuhiro,Kingston, David G. I.
, p. 5457 - 5460 (2007/10/02)
Racemic fecapentaene-12 and its regioisomer 2-(1,3,5,7,9-dodecapentaenyloxy)-1,3-propanediol (2) have been synthesized.The latter compound is comparably mutagenic to 1.
