958449-59-7Relevant articles and documents
Boron-Catalyzed N-Alkylation of Arylamines and Arylamides with Benzylic Alcohols
Guru, Murali Mohan,Thorve, Pradip Ramdas,Maji, Biplab
, p. 806 - 819 (2020)
A sustainable boron-based catalytic approach for chemoselective N-alkylation of primary and secondary aromatic amines and amides with primary, secondary, and tertiary benzylic alcohols has been presented. The metal-free protocol operates at low catalyst loading, tolerates several functional groups, and generates H2O as the sole byproduct. Preliminary mechanistic studies were performed to demonstrate the crucial role of boron catalyst for the activation of the intermediate dibenzyl ether and to identify the rate-determining step.
Development of a CuCl/phosphine system to catalyze phenylation and methylation of N-tosyl aldimines with phenylboronic andmethylboronic acids
Ashouri, Akram,Nasiri, Behzad,Pourian, Somayeh,Samadi, Saadi,Zamani, Hossein
, p. 575 - 581 (2021/01/13)
The addition of phenylboronic and methylboronic acids to activated aromatic aldimines was demonstrated in the presence of copper(I)-phosphine complexes. The desired products were obtained using copper chloride/phosphine, and potassium fluoride in under toluene reflux, in moderate-to-good yield and a suitable reaction time.
Metal-free direct N-benzylation of sulfonamides with benzyl alcohols by employing boron trifluoride-diethyl ether complex
Pan, Jing,Li, Jia-Qiang,Huang, Ruo-Feng,Zhang, Xiao-Hui,Shen, Hang,Xiong, Yan,Zhu, Xiang-Ming
supporting information, p. 1101 - 1108 (2015/04/14)
N-Benzylation of sulfonamides with both primary and secondary benzyl alcohols by employing boron trifluoride-diethyl ether complex under mild reaction conditions has been developed, which is an environmentally benign and facile protocol for assembling a series of primary and secondary benzyl sulfonamides in yields up to 83%. In this coupling reaction, the beneficial role of water has been clarified in detail through control experiments.
Highly enantioselective Rh-catalyzed transfer hydrogenation of N-sulfonyl ketimines
Kwak, Se Hun,Lee, Sun Ah,Lee, Kee-In
experimental part, p. 800 - 804 (2010/10/21)
Several imine species comprising N-sulfinyl and N-sulfonyl ketimine, oxime, and enamine derivatives were subjected to asymmetric transfer hydrogenation in an azeotropic mixture of formic acid/triethylamine. Among them, the Rh-catalyzed transfer hydrogenat