958457-25-5

Basic information

• Product Name: 3-benzyloxy-6-methyl-2-(O-tert-butyldimethylsily l)-hydroxymethyl-pyran-4(1H)-one
• Synonyms: 3-benzyloxy-6-methyl-2-(O-tert-butyldimethylsily l)-hydroxymethyl-pyran-4(1H)-one
• CAS NO: 958457-25-5
• Molecular Weight: 360.525
• Mol File: 958457-25-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-benzyloxy-6-methyl-2-(O-tert-butyldimethylsily l)-hydroxymethyl-pyran-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyloxy-6-methyl-2-(O-tert-butyldimethylsily l)-hydroxymethyl-pyran-4(1H)-one(958457-25-5)
• EPA Substance Registry System: 3-benzyloxy-6-methyl-2-(O-tert-butyldimethylsily l)-hydroxymethyl-pyran-4(1H)-one(958457-25-5)

Safety Data

• Hazardous Substances Data: 958457-25-5(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 216581-77-0 2-Hydroxymethyl-3-benzyloxy-6-methyl-pyran-4(1H)-one 

Downstream Products

• 958457-40-4 ethyl (2E)-3-{5-chloro-6-methyl-4-oxo-3-[4-(4-trifluoromethoxy-phenoxy)-phenyl]-1,4-dihydro-pyridinyl}-2-propenoate 
• 1257875-11-8 5-chloro-6'-[2-fluoro-4-(trifluoromethyl)phenyl]-2-(hydroxymethyl)-6-methyl-3,3'-bipyridin-4(1H)-one 
• 1257875-10-7 5-chloro-2-(hydroxymethyl)-6-methyl-6'-{4-[(trifluoromethyl)-oxy]phenyl}-3,3'-bipyridin-4(1H)-one 
• 1257875-20-9 2-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-3-{6-[2-fluoro-4-(trifluoromethyl)phenyl]-3-pyridinyl}-6-methyl-4H-pyran-4-one 
• 1257875-19-6 2-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-6-methyl-3-(6-{4-[(trifluoromethyl)oxy]phenyl}-3-pyridinyl)-4H-pyran-4-one 
• 1334392-78-7 C₂₂H₁₈ClF₃N₂O₄ 
• 1334393-02-0 C₂₄H₂₂ClF₃N₂O₄ 
• 1334393-00-8 C₂₄H₂₂ClF₃N₂O₃ 
• 1334392-98-1 C₂₂H₂₀ClF₃N₂O₃ 
• 1334392-75-4 C₂₀H₁₃ClF₃NO₅ 
• 958457-38-0 5-chloro-6-methyl-4-oxo-3-[4-({4-[(trifluoromethyl)oxy]phenyl}oxy)phenyl]-1,4-dihydro-2-pydinecarbaldehyde 
• 958457-29-9 6-methyl-2-(O-tert-butyldimethylsilyl)hydroxymethyl-3-(4-[3-(trifluoromethyl)phenyl]oxy)-pyran-4(1H)-one 
• 958457-28-8 6-methyl-2-(O-tert-butyldimethylsilyl)hydroxymethyl-3-(4-{4-[(trifluoromethyl)oxy]phenyl}oxy)-pyran-4(1H)-one 

Relevant articles and documents

Potent antimalarial 4-pyridones with improved physico-chemical properties

Antimalarial 4-pyridones are a novel class of inhibitors of the plasmodial mitochondrial electron transport chain targeting Cytochrome bc1 (complex III). In general, the most potent 4-pyridones are lipophilic molecules with poor solubility in aqueous medi

Novel heterocyclic compounds

4-pyridone derivatives of Formula I and pharmaceutically acceptable derivatives thereof, processes for their preparation, pharmaceutical formulations thereof and their use in chemotherapy of certain parasitic infections such as malaria, are provided.