958651-06-4

Upstream product

• 958651-01-9 1,1-dimethylethyl 4-[2-[1-(E)-3-(methyloxy)-3-oxo-1-propen-1-yl]-6-(phenylmethyl)-8-quinolinyl]-1-piperazinecarboxylate 
• 958651-00-8 1,1-dimethylethyl 4-{6-bromo-2-[1-(E)-3-(methyloxy)-3-oxo-1-propen-1-yl]-8-quinolinyl}-1-piperazinecarboxylate 
• 958651-02-0 methyl (2E) 3-[6-(phenylmethyl)-8-(1-piperazinyl)-2-quinolinyl]-2-propenoate 
• 955359-97-4 2-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)ethanol 
• 955359-96-3 2-[4-(3-chloropropoxy)phenyl]ethanol 
• 501-94-0 p-hydroxyphenethyl alcohol 
• 958650-99-2 1,1-dimethylethyl 4-(6-bromo-2-formyl-8-quinolinyl)-1-piperazinecarboxylate 
• 958650-97-0 1,1-dimethylethyl 4-(6-bromo-2-methyl-8-quinolinyl)-1-piperazinecarboxylate 
• 958650-94-7 6-bromo-8-fluoro-2-methylquinoline 
• 367-24-8 4-bromo-2-fluoroaniline 
• 958650-95-8 6-bromo-2-methyl-8-(1-piperazinyl)quinoline 
• 955359-98-5 2-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)ethyl methanesulfonate 
• 958651-04-2 methyl 3-[6-(phenylmethyl)-8-(1-piperazinyl)-2-quinolinyl]-propanoate 

Relevant academic research and scientific papers

The discovery of quinoline based single-ligand human H1and H3receptor antagonists

A novel series of potent quinoline-based human H1and H3bivalent histamine receptor antagonists, suitable for intranasal administration for the potential treatment of allergic rhinitis associated nasal congestion, were identified. Com

HISTAMINE RECEPTOR ANTAGONISTS COMPRISING AN AZEPIN CORE

The present invention relates to compounds of formula (I), and salts thereof, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders, such as allergic rhinitis.