958727-35-0Relevant academic research and scientific papers
Sulfonamides and sulphonyl ester of quinolines as non-acidic, nonsteroidal, anti-inflammatory agents
Bano, Bilquees,Kanwal,Khan, Khalid Mohammed,Jabeen, Almas,Faheem, Aisha,Taha, Muhammad,Haider, Syed Moazzam,Perveen, Shahnaz
, p. 112 - 120 (2021/04/21)
Background: Quinolines are an important class of heterocyclic compounds possessing a wide range of biological activities. Previously, we had identified Schiff bases of quinoline as potential anti-inflammatory agents, thus the current work is the continuat
Synthesis, in?vitro β-glucuronidase inhibitory potential and molecular docking studies of quinolines
Bano, Bilquees,Arshia,Khan, Khalid Mohammed,Kanwal,Fatima, Bibi,Taha, Muhammad,Ismail, Nor Hadiani,Wadood, Abdul,Ghufran, Mehreen,Perveen, Shahnaz
, p. 849 - 864 (2017/09/05)
In this study synthesis and β-glucuronidase inhibitory potential of 3/5/8 sulfonamide and 8-sulfonate derivatives of quinoline (1–40) are discussed. Studies reveal that all the synthetic compounds were found to have good inhibitory activity against β-gluc
Discovery and validation of a series of aryl sulfonamides as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP)
Dahl, Russell,Sergienko, Eduard A.,Su, Ying,Mostofi, Yalda S.,Yang, Li,Simao, Ana Maria,Narisawa, Sonoko,Brown, Brock,Mangravita-Novo, Arianna,Vicchiarelli, Michael,Smith, Layton H.,O'Neill, W. Charles,Millán, José Luis,Cosford, Nicholas D. P.
experimental part, p. 6919 - 6925 (2010/04/24)
We report the characterization and optimization of drug-like smallmolecule inhibitors of tissue-nonspecific alkaline phosphatase (TNAP), an enzyme critical for the regulation of extracellular matrix calcification during bone formation and growth.High-thro
