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METHYL 7-HYDROXY-2-NAPHTHOATE, a chemical compound belonging to the naphthoic acid family, is a derivative of 2-naphthoic acid with a methyl ester group at the 7th position and a hydroxy group at the 2nd position on the naphthalene ring. It is known for its light absorption and emission properties, making it a versatile compound in the chemical and pharmaceutical industries.

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  • 95901-05-6 Structure
  • Basic information

    1. Product Name: METHYL 7-HYDROXY-2-NAPHTHOATE
    2. Synonyms: METHYL 7-HYDROXY-2-NAPHTHOATE;Methyl 7-hydroxynaphthalene-2-carboxylate;ethyl 7-hydroxy-2-naphthoate
    3. CAS NO:95901-05-6
    4. Molecular Formula: C12H10O3
    5. Molecular Weight: 202.21
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 95901-05-6.mol
  • Chemical Properties

    1. Melting Point: 157-158 °C(Solv: toluene (108-88-3))
    2. Boiling Point: 368.5±15.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.264±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Inert atmosphere,Room Temperature
    8. Solubility: N/A
    9. PKA: 9.19±0.40(Predicted)
    10. CAS DataBase Reference: METHYL 7-HYDROXY-2-NAPHTHOATE(CAS DataBase Reference)
    11. NIST Chemistry Reference: METHYL 7-HYDROXY-2-NAPHTHOATE(95901-05-6)
    12. EPA Substance Registry System: METHYL 7-HYDROXY-2-NAPHTHOATE(95901-05-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 95901-05-6(Hazardous Substances Data)

95901-05-6 Usage

Uses

Used in Dye Production:
METHYL 7-HYDROXY-2-NAPHTHOATE is used as a dye intermediate for its ability to absorb and emit light, contributing to the color properties of various dyes.
Used in Pharmaceutical Industry:
METHYL 7-HYDROXY-2-NAPHTHOATE is used as an intermediate in the synthesis of organic compounds, playing a crucial role in the development of pharmaceutical products.
Used in Pigment Production:
METHYL 7-HYDROXY-2-NAPHTHOATE is used as a pigment intermediate, leveraging its light absorption and emission properties to enhance the color characteristics of pigments in various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 95901-05-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,9,0 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 95901-05:
(7*9)+(6*5)+(5*9)+(4*0)+(3*1)+(2*0)+(1*5)=146
146 % 10 = 6
So 95901-05-6 is a valid CAS Registry Number.

95901-05-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 7-hydroxynaphthalene-2-carboxylate

1.2 Other means of identification

Product number -
Other names 2-Naphthalenecarboxylic acid,7-hydroxy-,methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:95901-05-6 SDS

95901-05-6Relevant articles and documents

Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064

Akwabi-Ameyaw, Adwoa,Bass, Jonathan Y.,Caldwell, Richard D.,Caravella, Justin A.,Chen, Lihong,Creech, Katrina L.,Deaton, David N.,Jones, Stacey A.,Kaldor, Istvan,Liu, Yaping,Madauss, Kevin P.,Marr, Harry B.,McFadyen, Robert B.,Miller, Aaron B.,III, Frank Navas,Parks, Derek J.,Spearing, Paul K.,Todd, Dan,Williams, Shawn P.,Wisely, G. Bruce

experimental part, p. 4339 - 4343 (2009/04/06)

Starting from the known FXR agonist GW 4064 1a, a series of stilbene replacements were prepared. The 6-substituted 1-naphthoic acid 1b was an equipotent FXR agonist with improved developability parameters relative to 1a. Analog 1b also reduced the severit

VITAMIN D RECEPTOR MODULATORS

-

Page/Page column 34, (2008/06/13)

The present invention relates to novel, non-secosteroidal, phenyl-naphthalene compounds of Formula (I): wherein R, R1, RP, ZP, LP1, LP2 LNP, RP3, RN, and ZNP are defined herein, their prepa

NAPTHTHALENE DERIVATIVES WHICH INHIBIT THE CYTOKINE OR BIOLOGICAL ACTIVITY OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)

-

Page 83-84, (2010/02/04)

Where Y, R1-R8 and R101-R108 are as defined in the specification. Compounds of formula (II) and methods of inhibiting the cytokine or biological activity of Macrophage Migrating Inhibitory Factor (MIF) comprising contacting MIF with a compound of formula (I) are provided. The invention also relates to methods of treating diseases or conditions where MIF cytokine or biological activity is implicated comprising administration of compounds of formula (I), either alone or as part of a combination therapy.

NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION

-

, (2008/06/13)

Naphthalene amides of formula (I) wherein the substituent containing A is bound to the 6- or 7- position of the 2-naphthol system; the substituent containing B is bound to the benzene ring at any free position; R is hydrogen or methyl; R is hydrogen, fluorine, chlorine or -OCH3, which is bound to the naphthalene system at any positions except the 2- and the one occupied by the other substituent; R is hydrogen, fluorine, chlorine or bromine; A- is -CO-NR- or -NR-CO- group, wherein R is hydrogen or methyl; B is a 5-tetrazolyl or -COOR group, wherein R is hydrogen, a (C1-C4)-alkyl or a phenylalkyl group of less than 10 carbon atoms; m is 0 or 1; n and p are integers from 0 to 6, with the proviso that n + p is less or equal to 6; as well as the solvates and pharmaceutically acceptable salts thereof, have leukotriene antagonistic action.

Piperidine-renin inhibitors compounds with improved physicochemical properties

Gueller, Rolf,Binggeli, Alfred,Breu, Volker,Bur, Daniel,Fischli, Walter,Hirth, Georges,Jenny, Christian,Kansy, Manfred,Montavon, Francois,Mueller, Marcel,Oefner, Christian,Stadler, Heinz,Vieira, Eric,Wilhelm, Maurice,Wostl, Wolfgang,Maerki, Hans Peter

, p. 1403 - 1408 (2007/10/03)

Piperidine renin inhibitors with heterocyclic core modifications or hydrophilic attachments show improved physical properties (lower lipophilicity, improved solubility). Tetrahydroquinoline derivative rac-30 with a molecular weight of 517 and a log D((pH 7.4)) of 1.9 displays potent and long lasting blood pressure lowering effects after oral administration to sodium depleted conscious marmosets.

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