959312-83-5

Basic information

• Product Name: 2-(phenylsulfonyl)-1H-indole
• Synonyms: 2-(phenylsulfonyl)-1H-indole
• CAS NO: 959312-83-5
• Molecular Weight: 257.313
• Mol File: 959312-83-5.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2-(phenylsulfonyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenylsulfonyl)-1H-indole(959312-83-5)
• EPA Substance Registry System: 2-(phenylsulfonyl)-1H-indole(959312-83-5)

Safety Data

• Hazardous Substances Data: 959312-83-5(Hazardous Substances Data)

Upstream product

• 59-48-3 2-oxoindole 
• 496-30-0 indolin-2-thione 
• 120-72-9 indole 
• 1950-77-2 benzenesulfonyl iodide 
• 1212-08-4 S-Phenyl benzenethiosulfonate 
• 80-17-1 benzenesufonyl hydrazide 
• 26340-47-6 3-Iodo-1H-indole 
• 873-55-2 sodium benzenesulfonate 
• 100-42-5 styrene 
• 107558-34-9 Phenyl-o-nitrostyrylsulfon 
• 56069-39-7 diethyl phenylsulfonylmethylphosphonate 
• 3112-85-4 methylphenylsulfonate 
• 120517-31-9 5-chloro-2-(methylthio)-1H-indole 

Downstream Products

• 1243565-45-8 (R,S)-2-(2-phenylsulfonylindol-1-yl)propionic acid ethyl ester 
• 1243565-37-8 1-(2-phenyloxyethyl)-2-phenylsulfonylindole 
• 1243565-46-9 (R)-2-(2-phenylsulfonylindol-1-yl)propionic acid ethyl ester 
• 824-90-8 1-phenylbut-1-ene 
• 959082-23-6 1-(1-phenylbut-2-yl)-2-phenylsulfonylindole 
• 1243565-41-4 1-(1-phenylethyl)-2-phenylsulfonylindole 
• 1243565-34-5 1-(2-cyanoethyl)-2-phenylsulfonylindole 
• 1243565-39-0 1-hexyl-2-phenylsulfonylindole 

Relevant articles and documents

Synthesis of 2-(Arylthio)indolenines via Chemoselective Arylation of Thio-Oxindoles with Arynes

A chemoselective S-arylation reaction of thio-oxindoles with arynes is presented. The reaction was performed under mild conditions and provided a straightforward synthesis of 2-(arylthio)indolenines in good to excellent yields. Besides, this simple operat

The fast and efficient KI/H2O2 mediated 2-sulfonylation of indoles and N-methylpyrrole in water

The rapid and efficient KI/H2O2-mediated 2-sulfonylation of substituted indoles and N-methylpyrrole was established. The corresponding 2-sulfonylation products are synthesized from readily available sulfur sources, namely arylsulfonyl hydrazides, 4-methylbenzenesulfinic acid and sodium 4-methylbenzenesulfinate in good to excellent yields in only 5 min. Moreover, the aqueous solution of hydrogen peroxide is used as both oxidant and solvent. Mechanistic studies demonstrated that 2,3-diiodoindoline was the main sulfonylation intermediate.

Convenient KI-catalyzed regioselective synthesis of 2-sulfonylindoles using water as solvent

A convenient procedure is developed for the preparation of 2-sulfonylindoles from indoles and sodium sulfinates catalyzed by KI in water. This environmentally benign 2-sulfonylation of indoles proceeds efficiently under mild conditions, affording the products with high regioselectivity and in moderate to good yields.