95968-88-0

Upstream product

• 95969-41-8 1,5-dimethyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide 
• 2052-92-8 3-methyl-4-phenyl-pyridine 
• 74-88-4 methyl iodide 
• 13515-63-4 1,3-dimethyl-4-phenyl-1,2,5,6-tetrahydropyridine 

Downstream Products

• 95969-41-8 1,5-dimethyl-4-phenyl-1,2,3,6-tetrahydropyridine N-oxide 
• 13515-63-4 1,3-dimethyl-4-phenyl-1,2,5,6-tetrahydropyridine 

Relevant academic research and scientific papers

Conversion of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its 5-Methyl Analog into Pyridinium Salts

Monoamine oxidase B metabolizes 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP; 1) first to 1-methyl-4-phenyl-2,3-dihydropyridinium salt (MPDP+; 5), and then to 1-methyl-4-phenylpyridinium salt (MPP+; 7).Chemical synthesis of MPD

REDUCTION OF PHENYL-SUBSTITUTED PYRIDINIUM METHOIODIDES WITH SODIUM BOROHYDRIDE. FORMATION OF AMINE-BORANE COMPLEXES IN WATER.

Reduction of phenyl-substituted pyridinium methoiodides with sodium borohydride in water afforded besides the desired tetrahydropyridines substantial amounts of amine-borane complexes.Reduction in methanol afforded tetrahydropyridines in high yield, with almost no amine-boranes formed.