95969-15-6

Basic information

• Product Name: 1H-Indol-4-ol, 1-benzoyl-
• CAS NO: 95969-15-6
• Molecular Formula: C15H11NO2
• Molecular Weight: 237.258
• Mol File: 95969-15-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Indol-4-ol, 1-benzoyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indol-4-ol, 1-benzoyl-(95969-15-6)
• EPA Substance Registry System: 1H-Indol-4-ol, 1-benzoyl-(95969-15-6)

Safety Data

• Hazardous Substances Data: 95969-15-6(Hazardous Substances Data)

Usage

Structure

A benzoyl derivative of indol-4-ol, a naturally occurring compound found in certain plants and animals

Therapeutic applications

Potential anti-inflammatory and antioxidant properties

Usage

Commonly used as a building block in organic synthesis for the production of various pharmaceuticals and agrochemicals

Potential uses

Development of new drugs and other biologically active molecules

Upstream product

• 98-88-4 benzoyl chloride 
• 27866-52-0 4-oxo-N-benzoyl-4,5,6,7-tetrahydroindole 
• 27866-53-1 5-bromo-4-oxo-N-benzoyl-4,5,6,7-tetrahydroindole 

Downstream Products

• 2380-94-1 1H-indol-4-ol 

Relevant articles and documents

4-hydroxyindole preparation method suitable for industrial production

The invention relates to the technical field of organic synthesis, in particular to a preparation method of a medical intermediate 4-hydroxyindole. The method includes: taking 1, 5, 6, 7-tetrahydro-4H-indole-4-one as the raw material, carrying out nucleophilic substitution reaction under the action of alkali to obtain an amino protection product (I), reacting the compound (I) with a halogenation reagent to obtain alpha-halogenated ketone (II), subjecting the compound (II) to elimination reaction under the action of alkali to remove HX so as to obtain a 4-hydroxyindole derivative (III), and finally conducting hydrolysis deprotection on the compound (III) to obtain 4-hydroxyindole (IV). The invention provides a simple industrial production route for 4-hydroxyindole, and the method has the advantages of simple reaction operation, avoidance of high temperature, high pressure and catalytic reaction, and low cost.