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Upstream product

• 53087-13-1 3-(benzyloxy)phenyl bromide 
• 2043-61-0 cyclohexanecarbaldehyde 
• 24318-02-3 1-(benzyloxy)-3-chlorobenzene 
• 20967-96-8 2-(3-benzyloxyphenyl)acetonitrile 
• 111-24-0 1,5-dibromo-pentane 

Relevant academic research and scientific papers

Biaryl cannabinoid mimetics-Synthesis and structure-activity relationship

Synthesis, in vitro biological evaluation, and structure-activity relationships of a biaryl cannabinoid mimetic 2 are reported. Variations in the substitution pattern yielded a number of agonists with low nanomolar affinity. Replacing the phenol group by

A general method for the direct α-arylation of aldehydes with aryl bromides and chlorides

(Chemical Equation Presented) Wide scope: A catalyst system able to efficiently perform the title reaction is described (see scheme). The high level of activity achieved allows for the synthesis of highly functionalized compounds with a wide variety of substitution patterns under very mild conditions.