53087-13-1

Basic information

• Product Name: 3-BENZYLOXYBROMOBENZENE
• Synonyms: 1-BENZYLOXY-3-BROMOBENZENE;3-BROMOPHENYL BENZYL ETHER;3-BENZYLOXYBROMOBENZENE;BENZYL 3-BROMOPHENYL ETHER;3-Benzyloxybromobenzen;1-Bromo-3-benzyloxybenzene;1-Benzyloxy-3-broMobenzene,Benzyl 3-BroMophenyl Ether
• CAS NO: 53087-13-1
• Molecular Formula: C₁₃H₁₁BrO
• Molecular Weight: 263.13
• EINECS: 1308068-626-2
• Product Categories: Phenetole;Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds;Ethers;Organic Building Blocks;Oxygen Compounds;alkyl bromide
• Mol File: 53087-13-1.mol
• Article Data: 43

Chemical Properties

• Melting Point: 62°C
• Boiling Point: 333.5 °C at 760 mmHg
• Flash Point: 137.6 °C
• Appearance: White/Solid
• Density: 1.382 g/cm³
• Vapor Pressure: 0.000264mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-BENZYLOXYBROMOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYLOXYBROMOBENZENE(53087-13-1)
• EPA Substance Registry System: 3-BENZYLOXYBROMOBENZENE(53087-13-1)

Safety Data

• Hazard Codes: Xi,N
• Statements: 36/37/38-50/53-43-41
• Safety Statements: 26-36/37/39-50/53-43-41-61-60
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 53087-13-1(Hazardous Substances Data)

Usage

Chemical Properties

Whitetolightyellowcrystalpowde

InChI:InChI=1/C13H11BrO/c14-12-7-4-8-13(9-12)15-10-11-5-2-1-3-6-11/h1-9H,10H2

Upstream product

• 591-20-8 3-Bromophenol 
• 584-08-7 potassium carbonate 
• 100-44-7 benzyl chloride 
• 89598-96-9 (3-bromophenyl)boronic acid 
• 100-39-0 benzyl bromide 
• 585-79-5 m-nitrobromobenzene 
• 100-51-6 benzyl alcohol 

Downstream Products

• 156682-54-1 3-(benzyloxy)phenylboronic acid 
• 757961-91-4 (3-benzyloxy-phenyl)-(3,5-dimethoxy-phenyl)-methanol 
• 156668-96-1 1-[3-(phenylmethoxy)phenyl]undecanol 
• 133739-86-3 4-<3-(benzyloxy)phenyl>-4-hydroxy-3,4,5,6-tetrahydro-2H-pyran 
• 180182-08-5 3-(benzyloxy)cinnamaldehyde 
• 211495-56-6 1-(3-(benzyloxy)phenyl)cyclopentanol 
• 1370256-42-0 4-(3-hydroxyphenyl)piperidinium chloride 
• 1370256-39-5 1-benzyl-4-(3-hydoxyphenyl)-1,2,3,6-tetrahydropyridine 
• 1370256-40-8 C₁₈H₁₉NO*ClH 
• 188863-55-0 1-benzyl-4-[3-(benzyloxy)phenyl]-4-hydroxypiperidine 
• 946-80-5 (benzyloxy)benzene 
• 72216-35-4 3-fluorophenyl phenylmethyl ether 
• 403825-35-4 Magnesium 3-benzyloxyphenylsulfinate bromide 
• 850793-80-5 3-[4-(3-benzyloxy-phenoxy)-2-methyl-phenyl]propionic acid methyl ester 

Relevant articles and documents

ARYL SULFONAMIDES AS SMALL MOLECULE STAT3 INHIBITORS

The present disclosure provides pharmaceutical compositions comprising aryl sulfonamide Stat3 small molecule inhibitors and certain pharmaceutically acceptable salts thereof, and methods of their use for treating cancer.

An alternative route for boron phenoxide preparation from arylboronic acid and its application for C[sbnd]O bond formation

An efficient synthetic route to benzyl phenyl ether preparation has been successfully developed via a one-pot synthetic protocol utilizing a combination of arylboronic acids, hydrogen peroxide (H2O2), and benzyl halides. The whole procedure consists of two consecutive reactions, formation of boron phenoxide from arylboronic acids and its nucleophilic attack. A simple operation under mild conditions such as room-temperature ionic liquid (choline hydroxide), aerobic environment, and absence of metal- and base-catalysts has been employed. Expansion to utilize benzyl surrogates was also successfully accomplished.

NOVEL MODULATORS OF THE SIGMA-2 RECEPTOR AND THEIR METHOD OF USE

Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of sigma- 2 receptor activity.