959745-89-2Relevant academic research and scientific papers
Stereo- and regiocontrolled synthesis of highly functionalized cyclopentanes with multiple chiral centers
Nonn, Melinda,Binder, Adrienn,Volk, Balázs,Kiss, Loránd
, p. 1199 - 1209 (2020/03/17)
The synthesis of some highly substituted three-dimensional cyclopentanes with multiple chiral centers and with high regiochemical and stereochemical diversity has been accomplished starting from cyclopentadiene-derived aminocyclopentenecarboxylic acids. The small-molecular design consisted of stereo- and regiocontrolled functionalization of the starting cyclopentene β- and γ-amino acids through oxirane formation/oxirane opening and afforded regio- and diastereoisomers of orthogonally protected aminocyclopentanecarboxylates.
Substrate-dependent fluorinations of highly functionalized cycloalkanes
Kiss, Loránd,Remete, Attila Márió,Nonn, Melinda,Fustero, Santos,Sillanp??, Reijo,Fül?p, Ferenc
, p. 781 - 787 (2016/01/20)
Substrate-dependent fluorinations of several highly functionalized cycloalkanes with multiple stereocentres were investigated. The synthetic transformations were based on selective functionalization of the ring C=C bonds of the readily available bicyclic
Alkyne-azide cycloadditions with copper powder in a high-pressure continuous-flow reactor: High-temperature conditions versus the role of additives
Oetvoes, Sandor B.,Mandity, Istvan M.,Kiss, Lorand,Fueloep, Ferenc
, p. 800 - 808 (2013/05/09)
A safe and efficient flow-chemistry-based procedure is presented for 1,3-dipolar cycloaddition reactions between organic azides and acetylenes. This simple and inexpensive technique eliminates the need for costly special apparatus and utilizes Cu powder a
Diastereo- and enantioselective synthesis of orthogonally protected 2,4-diaminocyclopentanecarboxylates: A flip from β-amino- to β,γ-diaminocarboxylates
Kiss, Lorand,Forro, Eniko,Sillanpaeae, Reijo,Fueloep, Ferenc
, p. 8786 - 8790 (2008/03/13)
(Chemical Equation Presented) Conformationally restricted, orthogonally protected 2,4-diaminocarboxylates with a cyclopentane skeleton were efficiently synthesized from β-lactam 6, the syntheses involving strategies of diastereoselective epoxidation of th
