959775-03-2Relevant academic research and scientific papers
Formal synthesis of 14-membered unsymmetrical bis-macrolactone, (?)-colletodiol
Khomane, Navnath B.,Kumar, Rayala Naveen,Mali, Prakash R.,Shirsat, Prashishkumar K.,Meshram
supporting information, p. 4687 - 4690 (2017/11/17)
Formal synthesis of 14-membered unsymmetrical bis-macrolactone, (?)-colletodiol was accomplished from homopropargylic alcohol derivative. Building of the two different hydroxy acid fragments from the same intermediate of homoallylic alcohol was particular
RCM mediated synthesis of macrosphelides I and G
Sharma, Gangavaram V.M.,Veera Babu, Kagita
, p. 2175 - 2184 (2008/02/11)
The total synthesis of 16-membered macrolides, macraosphelides I and G, has been achieved starting from ethyl-(S)-lactate and (S)-malic acid. A combination of Jacobsen's hydrolytic kinetic resolution and Sharpless epoxidation is used for the creation of two stereogenic centres, while Yamaguchi esterification and ring-closing metathesis strategies were used for the construction of the lactone ring.
