959861-52-0Relevant academic research and scientific papers
GLYCOMIMETICS FOR USE FOR THE TREATMENT OF VASCULAR CALCIFICATION AND/OR ENDOTHELIAL DYSFUNCTION
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Page/Page column 65, (2017/03/28)
The present invention relates to the use of glycomimetic compounds for the treatment of vascular calcification and/or endothelial dysfunction, particularly the use of small molecule mimetics of heparin/heparan sulfate, such as compounds according to formula (A), (B), (C) or (D), or pharmaceutically acceptable derivatives thereof
Novel heparin/heparan sulfate mimics as inhibitors of HGF/SF-induced MET activation
Raiber, Eun-Ang,Wilkinson, James A.,Manetti, Fabrizio,Botta, Maurizio,Deakin, Jon,Gallagher, John,Lyon, Malcolm,Ducki, Sylvie W.
, p. 6321 - 6325 (2008/09/17)
The synthesis of simple, non-sugar glycosaminoglycan (GAG) mimics has been achieved and the analogues evaluated for their ability to inhibit the activation of the MET receptor by hepatocyte growth factor/scatter factor (HGF/SF).
