959911-89-8Relevant academic research and scientific papers
Stereospecific N-oxide-mediated monoprotection of trans-3,4-dihydroxypyrrolidine derivatives
Rejman, Dominik,Kocalka, Petr,Budesinsky, Milos,Barvik Jr., Ivan,Rosenberg, Ivan
, p. 2165 - 2174 (2008/02/11)
We found that the syntheses of O-monosubstituted 1-N-alkyl-trans-3,4-dihydroxypyrrolidines, normally faces serious obstacles due to poorly reactive hydroxy groups as a consequence of the presence of a highly basic pyrrolidine nitrogen atom, but that they
