959927-87-8Relevant academic research and scientific papers
Association of electroanalytical and spectrophotometric methods to evaluate the antioxidant activity of isobenzofuranone in primary cultures of hippocampal neurons
Coelho Nogueira, Katiane de Oliveira Pinto,Manhabosco, Taise Matte,Oliveira, Laser Ant?nio Machado,Pereira, Wagner Luiz,Ribeiro, Iara Mariana Lellis,Teixeira, Róbson Ricardo,de Brito, Ana Carolina Ferreira,dos Reis Teixeira, Aniely
, (2020/08/24)
The isobenzofuran-1(3H)-ones (phthalides) exhibit various biological activities, including antioxidant activity on reactive oxygen species (ROS). An excess of ROS that cannot be naturally contained by cellular enzymatic systems is called redox imbalance,
Nuclear Magnetic Resonance (NMR), Infrared (IR) and Mass Spectrometry (MS) study of keto-enol tautomerism of isobenzofuran-1(3H)-one derivatives
Pires, Diego Arantes Teixeira,Pereira, Wagner Luiz,Teixeira, Róbson Ricardo,Figueroa-Villar, José Daniel,Nascimento, Claudia Jorge Do
, p. 146 - 152 (2016/03/01)
The keto-enol tautomerism of 3-(2-hydroxy-4,4-dimethyl-6-oxo-cyclohexen-1-yl)isobenzofuran-1(3H-one (1), 3-(2-hydroxy-6-oxocyclohex-1-enyl)isobenzofuran-1(3H)-one (2), 3-(2-hydroxy-4-methyl-6-oxocyclohex-1-enyl)isobenzofuran-1(3H)-one (3), 3-(2-hydroxy-5-
Synthesis and antiproliferative activity of C-3 functionalized isobenzofuran-1(3H)-ones
Teixeira, Robson Ricardo,Bressan, Gustavo Costa,Pereira, Wagner Luiz,Joana Gasperazzo Ferreira,De Oliveira, Fabricio Marques,Thomaz, Deborah Campos
, p. 1881 - 1896 (2013/04/23)
A series of thirteen C-3 functionalized isobenzofuran-1(3H)-ones (phtalides) was synthesized via condensation, aromatization, and acetylation reactions. NMR (one and two dimensional experiments), IR, and mass spectrometry analysis allowed confirmation of
Synthetic analogues of the natural compound cryphonectric acid interfere with photosynthetic machinery through two different mechanisms
Teixeira, Róbson Ricardo,Pereira, Wagner Luiz,Tomaz, Deborah Campos,De Oliveira, Fabrício Marques,Giberti, Samuele,Forlani, Giuseppe
, p. 5540 - 5549 (2013/07/27)
A series of isobenzofuran-1(3H)-ones (phthalides), analogues of the naturally occurring phytotoxin cryphonectric acid, were designed, synthesized, and fully characterized by NMR, IR, and MS analyses. Their synthesis was achieved via condensation, aromatiz
Regiospecific synthesis of 3-(2,6-dihydroxyphenyl)phthalides: application to the synthesis of isopestacin and cryphonectric acid
Mal, Dipakranjan,Pahari, Pallab,De, Saroj Ranjan
, p. 11781 - 11792 (2008/03/13)
DBU catalyzed condensation of phthalaldehydic acids and 1,3-diketones has been developed to be a general method for the synthesis of 3-substituted phthalides. This method, in combination with mercuric acetate mediated oxidative aromatization has been util
