959936-91-5Relevant academic research and scientific papers
Asymmetric intermolecular cyclopropanation of alkenes by diazoketones catalyzed by Halterman iron porphyrins
Nicolas, Irène,Roisnel, Thierry,Maux, Paul Le,Simonneaux, Gérard
scheme or table, p. 5149 - 5151 (2009/12/05)
The asymmetric addition of diazoacetophenone to styrene derivatives to give optically active cyclopropyl ketones (ee up to 80%) was carried out using chiral iron porphyrins as homogeneous catalysts. Intermolecular N-H functionalization of anilines by mean
Catalytic asymmetric cyclopropanation of enones with dimethyloxosulfonium methylide promoted by a La-Li3-(Biphenyldiolate)3 + NaI complex
Kakei, Hiroyuki,Sone, Toshihiko,Sohtome, Yoshihiro,Matsunaga, Shigeki,Shibasaki, Masakatsu
, p. 13410 - 13411 (2008/09/17)
Catalytic asymmetric cyclopropanation of enones with dimethyloxosulfonium methylide using a La-Li3-(biphenyldiolate)3 + NaI complex is described. The present method is complementary to the previously reported catalytic enantioselective methods in terms of ylides used, and trans products were exclusively obtained in good yield (96-73%) and high enantioselectivity (99-84% ee). Use of biphenyldiol 1b-H2 and NaI additive was essential to achieve high enantioselectivity. Copyright
