959937-98-5

Basic information

• Product Name: (R)-1-[(2S,5R)-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulphonyl)piperidin-2-yl]-3-methylbutan-2-ol
• Synonyms: (R)-1-[(2S,5R)-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulphonyl)piperidin-2-yl]-3-methylbutan-2-ol
• CAS NO: 959937-98-5
• Molecular Weight: 560.755
• Mol File: 959937-98-5.mol

Chemical Properties

• CAS DataBase Reference: (R)-1-[(2S,5R)-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulphonyl)piperidin-2-yl]-3-methylbutan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-[(2S,5R)-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulphonyl)piperidin-2-yl]-3-methylbutan-2-ol(959937-98-5)
• EPA Substance Registry System: (R)-1-[(2S,5R)-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulphonyl)piperidin-2-yl]-3-methylbutan-2-ol(959937-98-5)

Safety Data

• Hazardous Substances Data: 959937-98-5(Hazardous Substances Data)

Upstream product

• 959937-51-0 benzyl (2S,5R)-5-hydroxy-6-oxopiperidine-2-carboxylate 
• 959937-50-9 (3R,6S)-6-hydroxymethyl-1-(toluene-4-sulphonyl)piperidin-3-ol 
• 959937-49-6 (3R,6S)-1-(toluene-4-sulphonyl)-6-triisopropylsilanyloxymethylpiperidin-3-ol 
• 959937-46-3 [(2S,5R)-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulphonyl)piperidin-2-yl]methanol 
• 959937-44-1 [(2S,5R)-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulphonyl)piperidin-2-yl]acetonitrile 
• 959937-45-2 (2S,5R)-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulphonyl)piperidin-2-ylmethyl methanesulphonate 
• 959937-48-5 4-(3-methoxypropyl)-6-[(3R,6S)-1-(toluene-4-sulphonyl)-6-triisopropylsilanyloxy-methylpiperidin-3-yloxymethyl]-4H-benzo[1,4]oxazin-3-one 
• 959937-47-4 4-(3-methoxypropyl)-6-[(3R,6S)-1-(toluene-4-sulphonyl)-6-triisopropylsilanyloxy-methylpiperidin-3-yloxymethyl]-3,4-dihydro-2H-benzo[1,4]oxazine 
• 406945-58-2 1,3,4-trideoxynojirimycin 
• 480460-75-1 2-benzyl 1-tert-butyl (2S,5R)-5-hydroxy-6-oxo-1,2-piperidinedicarboxylate 
• 959937-43-0 [(2S,5R)-5-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-1-(toluene-4-sulphonyl)piperidin-2-yl]acetaldehyde 
• 1068-55-9 isopropylmagnesium chloride 

Relevant articles and documents

SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS

Use of compounds of the general formula (I) and pharmaceutically acceptable salt thereof, in which R, R1 and X have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin Il and/or HIV protease inhibitors.

2,5-DISUBSTITUTED PIPERIDINES

The application relates to 2,5-disubstituted piperidines, their preparation and use as medicines, especially as renin inhibitors, of the general formula (I) in which R, R1 and X are each as defined in detail in the description, and pharmaceutical preparations comprising these compounds.