960004-32-4Relevant academic research and scientific papers
"On-water" Michael-type addition reactions promoted by PhSeZnCl
Battistelli, Benedetta,Lorenzo, Testaferri,Tiecco, Marcello,Santi, Claudio
experimental part, p. 1848 - 1851 (2011/05/05)
In this communication we report that our reagent PhSeZnCl can be conveniently used to effect Michael addition like reactions of unsaturated ketones and electron-deficient alkynes, leading to synthetically useful β-seleno derivativesand vinyl selenides, respectively. The reactions are effected at room temperature in THF as well as under "on water" conditions. When the addition occurs on a triple bond, good stereoselectivity is observed, and the reaction shows a rate acceleration in water suspension. Copyright
