960041-86-5Relevant academic research and scientific papers
Aspartic protease inhibitors via C1-homologation of peptidic aldehydes and studies on reduced amide isosteres
Braun, Hannes A.,Zall, Andrea,Brockhaus, Manfred,Schütz, Marco,Meusinger, Reinhard,Schmidt, Boris
, p. 7990 - 7993 (2008/03/14)
(R)-Configured isophthalic hydroxyethylamines play an important role in the inhibition of β-secretase (BACE1). We present the synthesis of a number of (S)-configured hydroxyethylamine derivatives via 2-iodoethanol intermediates and the comparison with the
