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CAS

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960067-77-0

4-bromo-N-(2-dimethylaminoethyl)-2-fluoro-benzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 960067-77-0 Structure

  • Basic information

    1. Product Name: 4-bromo-N-(2-dimethylaminoethyl)-2-fluoro-benzamide
    2. Synonyms: 4-bromo-N-(2-dimethylaminoethyl)-2-fluoro-benzamide
    3. CAS NO:960067-77-0
    4. Molecular Formula:
    5. Molecular Weight: 289.147
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 960067-77-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-bromo-N-(2-dimethylaminoethyl)-2-fluoro-benzamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-bromo-N-(2-dimethylaminoethyl)-2-fluoro-benzamide(960067-77-0)
    11. EPA Substance Registry System: 4-bromo-N-(2-dimethylaminoethyl)-2-fluoro-benzamide(960067-77-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 960067-77-0(Hazardous Substances Data)

960067-77-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 960067-77-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,6,0,0,6 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 960067-77:
(8*9)+(7*6)+(6*0)+(5*0)+(4*6)+(3*7)+(2*7)+(1*7)=180
180 % 10 = 0
So 960067-77-0 is a valid CAS Registry Number.

960067-77-0Downstream Products

960067-77-0Relevant articles and documents

HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES

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Paragraph 00251, (2016/05/02)

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions in need of inhibition of heparan sulfate biosynthesis.

The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing

Jones, Clifford D.,Andrews, David M.,Barker, Andrew J.,Blades, Kevin,Daunt, Paula,East, Simon,Geh, Catherine,Graham, Mark A.,Johnson, Keith M.,Loddick, Sarah A.,McFarland, Heather M.,McGregor, Alexandra,Moss, Louise,Rudge, David A.,Simpson, Peter B.,Swain, Michael L.,Tam, Kin Y.,Tucker, Julie A.,Walker, Mike

body text, p. 6369 - 6373 (2009/10/01)

The development of a novel series of imidazole pyrimidine amides as cyclin-dependent kinase (CDK) inhibitors is described. Optimisation of inhibitory potency against multiple CDK's (1, 2 and 9) resulted in imidazole pyrimidine amides with potent in vitro anti-proliferative effects against a range of cancer cell lines. Excellent physiochemical properties and large margins against inhibition of CYP isoforms and the hERG ion channel were achieved by modification of lipophilicity and amine basicity. A candidate with disease model activity in human cancer cell line xenografts and with suitable physiochemical and pharmacokinetic profiles for intravenous (iv) dosing was selected for further development as AZD5597.

CHEMICAL COMPOUNDS

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Page/Page column 33, (2008/06/13)

Compounds of formula (I) which possess cell cycle inhibitory activity are described.

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