960069-01-6

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 705-76-0 3,5-dimethoxybenzyl alcohol 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 57179-35-8 3-hydroxy-5-methoxybenzaldehyde 

Downstream Products

• 960069-20-9 C₃₂H₃₄O₃Si 
• 960069-19-6 C₃₁H₃₂O₃Si 

Relevant academic research and scientific papers

SKIN LIGHTENING COMPOUNDS

The present invention provides a compound of Formula I, II or III or a salt or prodrug derivative thereof that is a skin-lightening agent useful for the inhibition of melanin synthesis and/or the removal of existing melanin to function as a skin-lightening agent.

First application of an efficient and versatile ligand for copper-catalyzed cross-coupling reactions of vinyl halides with N-heterocycles and phenols

[Chemical equaction presented] 2-Pyridin-2-yl-1H-benzoimidazole L3 is presented as a new, efficient, and versatile bidentate N-donor ligand suitable for the copper-catalyzed formation of vinyl C N and C O bonds. This inexpensive and easily prepared ligand facilitates copper-catalyzed cross-coupling reactions of alkenyl bromides and Iodldes with N-heterocycles and phenols to afford the desired cross-coupled products In good to excellent yields with full retention of stereochemistry. This method is particularly noteworthy given Its efficiency, that is, mild reaction conditions, low catalyst loading, simplicity, versatility, and exceptional level of functional group tolerance.