960121-91-9

Upstream product

• 169447-70-5 (S)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester 
• 555-16-8 4-nitrobenzaldehdye 
• 960121-90-8 1,1-dimethylethyl (2S)-2-methyl-4-[(4-nitrophenyl)methyl]-1-piperazinecarboxylate 

Downstream Products

• 960121-92-0 1,1-dimethylethyl (2S)-2-methyl-4-{[4-(methylamino)phenyl]methyl}-1-piperazinecarboxylate 
• 960122-35-4 1,1-dimethylethyl (2S)-4-({4-[{[4-(4-fluorophenyl)-1-piperidinyl]carbonyl}(methyl)amino]phenyl}methyl)-2-methyl-1-piperazinecarboxylate 
• 960122-08-1 1,1-dimethylethyl (2S)-4-({4-[({4-[(3-fluorophenyl)amino]-1-piperidinyl}carbonyl)(methyl)amino]phenyl}methyl)-2-methyl-1-piperazinecarboxylate 
• 1158989-68-4 1,1-dimethylethyl (2S)-4-[(4-{[(4'-fluoro-4-biphenylyl)sulfonyl]amino}phenyl)methyl]-2-methyl-1-piperazinecarboxylate 
• 1000812-96-3 1,1-dimethylethyl (2S)-2-methyl-4-[(4-{[2-(methyloxy)ethyl]amino}phenyl)methyl]-1-piperazinecarboxylate 
• 1000812-95-2 1,1-dimethylethyl (2S)-4-{[4-(ethylamino)phenyl]methyl}-2-methyl-1-piperazinecarboxylate 
• 1000812-94-1 1,1-dimethylethyl (2S)-2-methyl-4-({4-[(1-methylethyl)amino]phenyl}methyl)-1-piperazinecarboxylate 

Relevant academic research and scientific papers

PIPERAZINYL-SULFONAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES

The present invention relates to novel motilin agonists of formula (IA), processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.

PIPERAZINYL DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES

The invention relates to compounds of formula (I), processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions or disorders which are mediated via the GPR38 receptor.

BENZYLPIPERAZINE DERIVATIVES AS MOTILIN RECEPTOR ANTAGONISTS

The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions or disorders which are mediated via the GPR38 receptor.