960156-75-6Relevant academic research and scientific papers
Synthesis of polysubstituted α-pyrones using zinc-catalyzed addition-cyclization reactions
Liu, Wei-Bing,Chen, Cui,Zhang, Qing,Zhu, Zhi-Bo
, p. 1541 - 1544 (2015/04/27)
Various polysubstituted α-pyrone derivatives have been directly synthesized via a hydroalkylation of Michael additional reaction following a cyclized process catalyzed by the Lewis acid of Zn(OAc)2. This protocol provides a new convenient and s
Divergent NHC-catalyzed oxidative transformations of 3-bromoenal: Selective synthesis of 2H-pyran-2-ones and chiral dihydropyranones
Wang, Gang,Chen, Xia,Miao, Gaohan,Yao, Weijun,Ma, Cheng
, p. 6223 - 6232 (2013/07/26)
A selective synthesis of either 2H-pyran-2-ones (4) or chiral dihydropyranones (6) from the same substrates of 3-bromoenals and 1,3-dicarbonyl compounds upon oxidative N-heterocyclic carbene catalysis is presented. It is shown that the oxidative transformation of 3-bromoenals under NHC catalyst can be well controlled to proceed through two pathways, i.e., elimination of reducible β-bromide or by an external oxidant 3, allowing the selective generation two sorts of unsaturated acyl azoliums, respectively.
Hydroalkylation leading to heterocyclic compounds. Part 1: New strategies for the synthesis of polysubstituted 2H-pyran-2-ones
Liu, Wei-Bing,Jiang, Huan-Feng,Qiao, Chun-Li
experimental part, p. 2110 - 2115 (2009/07/11)
Polysubstituted 2H-pyran-2-ones and 5,6-dihydro-2H-pyran-2-ones were synthesized via the MCRs initiated by the hydroalkylation of alkynoates with activated methylenes. Under the optimized reaction conditions, the desired products were obtained in 47-88% i
