960212-26-4Relevant academic research and scientific papers
Continuous fluorometric assays for acetylcholinesterase activity and inhibition with conjugated polyelectrolytes
Feng, Fude,Tang, Yanli,Wang, Shu,Li, Yuliang,Zhu, Daoben
, p. 7882 - 7886 (2008/09/18)
(Figure Presented) Quick but sensitive: A super-quenched fluorogenic complex of a cationic acetylcholine (ACh) derivative with an energy-acceptor tag and an anionic water-soluble conjugated polymer forms the basis of a highly effective fluorescence turn-on assay for studying the enzyme kinetics and inhibition of acetylcholinesterase (AChE; see schematic representation of the assay). FRET = fluorescence resonant energy transfer.
