96022-80-9Relevant academic research and scientific papers
Synthesis of 2'-deoxyisoinosine and related 2'-deoxyribonucleosides
Seela,Chen,Bindig,Kazimierczuk
, p. 194 - 202 (2007/10/02)
Various 2-substituted purine and pyrrolo[2,3-d]pyrimidine 2'-deoxyribonucleosides with methylthio (13a), chloro (13b), methoxy (9b), and oxo (2, 3) substituents at C(2) are prepared. They are obtained either via stereoselective nucleobase-anion glycosylation or by base transformation. A three-step synthesis of the unknown 2'-deoxyisoinosine (2) from 2'-deoxyguanosine (15) is described. Compound 2 as well as its 7-deazapurine derivative 3 exhibit strong fluorescence.
7-Deaza Isosters of 2'-Deoxyxanthosine and 2'-Deoxyspongosine - Synthesis via Glycosylation of 2,4-Dichloro-7H-pyrrolopyrimidine
Seela, Frank,Driller, Hansjuergen,Liman, Ulrich
, p. 312 - 320 (2007/10/02)
7-Deaza-2'-deoxyxanthosine (1a) and 7-deaza-2'-deoxyspongosine (2), two new pyrrolopyrimidine deoxynucleosides, have been prepared by nucleophilic displacement of the chloro substituents of the intermediate 2,4-dichloro-7-2-deoxy-3,5-di-O-(p-toluo
