90057-08-2

Basic information

• Product Name: 6-CHLORO-2-METHOXY-7-DEAZAPURINE
• Synonyms: 4-chloro-2-Methoxy-7H-pyrrolo[2,3-d]pyriMidine;4-Chloro-2-Methoxy-1H-pyrrolo[2,3-d]pyriMidine
• CAS NO: 90057-08-2
• Molecular Formula: C₇H₆ClN₃O
• Molecular Weight: 183.597
• Product Categories: Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides
• Mol File: 90057-08-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 180-185°C
• Boiling Point: 378.6°C at 760 mmHg
• Flash Point: 182.7°C
• Appearance: /
• Density: 1.477g/cm³
• Vapor Pressure: 1.36E-05mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: -20°C Freezer
• PKA: 10.02±0.20(Predicted)
• CAS DataBase Reference: 6-CHLORO-2-METHOXY-7-DEAZAPURINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-2-METHOXY-7-DEAZAPURINE(90057-08-2)
• EPA Substance Registry System: 6-CHLORO-2-METHOXY-7-DEAZAPURINE(90057-08-2)

Safety Data

• Hazardous Substances Data: 90057-08-2(Hazardous Substances Data)

Usage

Chemical Properties

Off-White to Pale Yellow Solid

Uses

6-Chloro-2-methoxy-7-deazapurine (cas# 90057-08-2) is a compound useful in organic synthesis.

InChI:InChI=1/C7H6ClN3O/c1-12-7-10-5(8)4-2-3-9-6(4)11-7/h2-3H,1H3,(H,9,10,11)

Upstream product

• 52133-67-2 ethyl 2-cyano-4,4-diethoxybutyrate 
• 90057-07-1 3,4-dihydro-2-methoxy-4-oxo-7H-pyrrolo<2,3-d>pyrimidine 

Downstream Products

• 1093800-34-0 C₂HF₃O₂*C₂₃H₂₉ClN₆O₅ 
• 1093799-55-3 C₂₈H₃₇ClN₆O₇ 
• 1092524-63-4 4-chloro-7-(2-ethoxycarbonylethyl)-2-methoxy-7H-pyrrolo[2,3-d]pyrimidine 
• 155532-17-5 7-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-2-methoxy-7H-pyrrolo<2,3-d>pyrimidine 
• 148214-62-4 2-methoxy-7H-pyrrolo<2,3-d>pyrimidine 
• 96022-80-9 4-Chlor-7-<2-desoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl>-2-methox-7H-pyrrolo<2,3-d>pyrimidin 
• 96022-81-0 4-Chlor-7-<2-desoxy-3,5-di-O-(p-toluoyl)-α-D-erythro-pentofuranosyl>-2-methoxy-7H-pyrrolo<2,3-d>pyrimidin 
• 90057-09-3 2,4-dimethoxy-7H-pyrrolo<2,3-d>pyrimidine 

Relevant articles and documents

Preparation method for catalyzing pyrimidine cyclic hydroxyl chlorination by tetraethylammonium chloride

The invention discloses a preparation method for catalyzing pyrimidine cyclic hydroxyl chlorination by tetraethylammonium chloride, which comprises the following steps: (1) adding phosphorus oxychloride into a container, adding tetraethylammonium chloride as a catalyst, adding a pyrimidine cyclic hydroxyl compound, and heating to react; (2) preparing an alkali liquor, cooling to 0 DEG C, and slowly dropwise adding an obtained reaction liquid into the alkali liquor for quenching to obtain a target product. The method has the advantages that the provided pyrimidine cyclic hydroxyl chlorination catalysis method is small in environmental pollution, the obtained product is light in color, the catalysis efficiency is high, and the phosphorus oxychloride recovery pressure is small.