960306-78-9Relevant academic research and scientific papers
Deproto-metallation using a mixed lithium-zinc base and computed CH acidity of 1-aryl 1H-benzotriazoles and 1-aryl 1H-indazoles
Nagaradja, Elisabeth,Chevallier, Floris,Roisnel, Thierry,Dorcet, Vincent,Halauko, Yury S.,Ivashkevich, Oleg A.,Matulis, Vadim E.,Mongin, Florence
, p. 1475 - 1487 (2014/03/21)
1-Aryl-1H-benzotriazoles and -1H-indazoles were synthesized, and their deproto-metallation using the base prepared by mixing LiTMP with ZnCl 2·TMEDA (1/3 equiv.) was studied. In the indazole series, reactions occurring at the 3 position were fo
Benzyne click chemistry with in situ generated aromatic azides
Zhang, Fengzhi,Moses, John E.
supporting information; experimental part, p. 1587 - 1590 (2009/08/07)
An efficient synthesis of substituted benzotriazoles using an azide-alkyne 1,3-dipolar cycloaddition "click reaction" is described. Key to the procedure is the in situ generation of the reactive aromatic azide and benzyne reaction partners.
