960307-47-5

Upstream product

• 6485-40-1 (R)-Carvone 
• 1216963-74-4 lithium acetylide-ethylenediamine complex 

Downstream Products

• 278799-72-7 (+)-(5S)-3-ethynyl-5-isopropenyl-2-methylcyclohex-2-enone 
• 278799-73-8 (+)-(1S,5S)-3-ethynyl-5-isopropenyl-2-methylcyclohex-2-enol 
• 278799-79-4 (3S,5S)-3-[(tert-butyldimethylsilyl)oxy]-1-ehtynyl-5-hydroxy-2-methylcyclohex-1-ene 
• 278799-78-3 (+)-(1S,5S)-3-ethynyl-5-isopropenyl-2-methylcyclohex-2-enyl tert-butyldimethylsilyl ether 
• 278801-11-9 (+)-(1S,5S)-5-(tert-butyldimethylsilyloxy)-3-ethynyl-4-methylcyclohex-3-enyl acetate 
• 278799-74-9 (+)-(1R,5S)-3-ethynyl-5-isopropenyl-2-methylcyclohex-2-enyl benzoate 
• 278799-76-1 (+)-(1S,5S)-3-ethynyl-5-isopropenyl-2-methylcyclohex-2-enyl benzoate 

Relevant academic research and scientific papers

The gold(I)- and silver(I)-catalyzed nicholas reaction

The Au(I) and Ag(I) catalytic Nicholas type reaction has been developed for oxygen and carbon nucleophiles. This process occurs with high reaction yields and selectivity, avoiding the main shortcomings of the acid-promoted standard Nicholas reaction. A catalytic reaction pathway involving trimetallic complex intermediates is proposed.

An enantiospecific strategy to all four diastereomers of A-ring enyne synthon of 1α,25-dihydroxyvitamin D3

Enantiospecific syntheses of derivatives all the four diastereomers of A-ring enyne synthon of 1α,25-dihydroxyvitamin D3 (5-ethynyl-4-methylcyclohex-4-en-1,3-diol) have been described starting from the abundantly available monoterpene (R)-carvo