278799-79-4

Upstream product

• 278801-11-9 (+)-(1S,5S)-5-(tert-butyldimethylsilyloxy)-3-ethynyl-4-methylcyclohex-3-enyl acetate 
• 278799-71-6 (5R)-1-ethynyl-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ol 
• 278799-78-3 (+)-(1S,5S)-3-ethynyl-5-isopropenyl-2-methylcyclohex-2-enyl tert-butyldimethylsilyl ether 
• 278799-73-8 (+)-(1S,5S)-3-ethynyl-5-isopropenyl-2-methylcyclohex-2-enol 
• 278799-72-7 (+)-(5S)-3-ethynyl-5-isopropenyl-2-methylcyclohex-2-enone 
• 497067-33-1 (3S,5S)-3-[(tert-butyldimethylsilyl)oxy]-1-ehtynyl-2-methyl-5-[(4-nitrophenyl)carbonyloxy]cyclohex-1-ene 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 115540-15-3 (1S,5R)-5-acetoxy-1-ethynyl-3-hydroxy-2-methylcyclohex-1-ene 
• 122172-37-6 (3S,5R)-5-acetoxy-3-<(tert-butyldimethylsilyl)oxy>-1-ethynyl-2-methylcyclohex-1-ene 
• 122172-46-7 (3S,5R)-3-<(tert-butyldimethylsilyl)oxy>-1-ethynyl-5-hydroxy-2-methylcyclohex-1-ene 
• 960307-47-5 (1R,5S)-1-ethynyl-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enol 

Downstream Products

• 497067-40-0 (3S,5R)-3-[(tert-buthyldimethylsilyl)oxy]-1-ethynyl-2-methyl-5-phthalimidocyclohex-1-ene 
• 497067-61-5 3β-[(tert-butoxycarbonyl)amino]-3-deoxy-1α,25-dihydroxyvitamin D₃ 
• 497067-55-7 3β-[(tert-butoxycarbonyl)amino]-3-deoxy-1α,25-dihydroxy-6,7-dehydroprevitamin D₃ 
• 1026054-40-9 3β-[(tert-butoxycarbonyl)amino]-3-deoxy-1α,25-dihydroprevitamin D₃ 
• 497067-43-3 (3S,5R)-5-[(tert-butoxycarbonyl)amino]-3-[(tert-butyldimethylsilyl)oxy]-1-ethynyl-2-methylcyclohex-1-ene 

Relevant academic research and scientific papers

An enantiospecific strategy to all four diastereomers of A-ring enyne synthon of 1α,25-dihydroxyvitamin D3

Enantiospecific syntheses of derivatives all the four diastereomers of A-ring enyne synthon of 1α,25-dihydroxyvitamin D3 (5-ethynyl-4-methylcyclohex-4-en-1,3-diol) have been described starting from the abundantly available monoterpene (R)-carvo

Efficient synthesis of novel 1α-amino and 3β-amino analogues of 1α,25-dihydroxyvitamin D3

Convenient synthetic routes to 1α-amino-25-hydroxyvitamin D3 (3) and 3β-amino-3-deoxy-1α,25-dihydroxyvitamin D3 (4), novel analogues of vitamin D3 bearing an amino group at the C-1 or C-3 position, have been developed starting from (S)-(+)-carvone. Construction of the A-ring fragments was accomplished by selective enzymatic hydrolysis of a diester intermediate and introduction of the amino group under Mitsunobu conditions.

A simple, enantiospecific approach to both enantiomers of 1α,25- dihydroxyvitamin D3 A-ring precursors from R-carvone

A simple and direct approach to both enantiomeric series of A-ring derivatives of 1α,25-dihydroxyvitamin D3 and the corresponding 1α,3α- derivatives, starting from the abundantly available R-carvone, is described. (C) 2000 Elsevier Science Ltd.