960314-97-0Relevant academic research and scientific papers
Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins
Tichenor, Mark S.,MacMillan, Karen S.,Stover, James S.,Wolkenberg, Scott E.,Pavani, Maria G.,Zanella, Lorenzo,Zaid, Abdel N.,Spalluto, Gianpiero,Rayl, Thomas J.,Hwang, Inkyu,Baraldi, Pier Giovanni,Boger, Dale L.
, p. 14092 - 14099 (2008/09/17)
The design, synthesis, and evaluation of a predictably more potent analogue of CC-1065 entailing the substitution replacement of a single skeleton atom in the alkylation subunit are disclosed and were conducted on the basis of design principles that emerg
