960370-97-2

Usage

Bicyclic structure

Cyclopropyl and cyclohexane rings
The compound has a three-membered cyclopropyl ring and a six-membered cyclohexane ring.

Functional groups

Cyclopropyl and carbonyl group
The compound contains a cyclopropyl group (a cyclic alkyl group) and a carbonyl group (a carbon-oxygen double bond).

Versatile reactivity

Synthesis of pharmaceuticals and agrochemicals
Due to its unique reactivity, the compound is commonly used in the synthesis of drugs and pesticides.

Development of new drugs and pesticides

Unique structure and reactivity
The compound's structure and reactivity make it useful in creating new therapeutic and pesticidal agents.

Building block in organic chemistry

Synthesis of complex molecules
1-Cyclopropyl-4-oxo-cyclohexanecarbonitrile can be used as a starting material for synthesizing more complex organic molecules.

Potential risks

Human health and environment
Proper handling of the compound is necessary as it may pose risks to human health and the environment.

Upstream product

• 960370-95-0 8-cyclopropyl-1,4-dioxa-spiro[4.5]decane-8-carbonitrile 
• 4746-97-8 cyclohexanedione monoethylene ketal 

Downstream Products

• 960370-99-4 C₁₃H₂₀N₂ 

Relevant academic research and scientific papers

Novel method for synthesis of compound 1-cyclopropyl-1-cyano-4-cyclohexanone

The invention discloses a novel method for synthesis of a compound 1-cyclopropyl-1-cyano-4-cyclohexanone. The method comprises that p-toluenesulfonylmethyl isocyanide and a compound 1, 4-dioxospiro[4, 5]decane-8-one shown in the formula 1 undergo a reacti

Optimization of novel di-substituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitors

Novel 4,4-disubstituted cyclohexylbenzamide inhibitors of 11β-HSD1 were optimized to account for liabilities relating to in vitro pharmacokinetics, cytotoxicity and protein-related shifts in potency. A representative compound showing favorable in vivo pharmacokinetics was found to be an efficacious inhibitor of 11β-HSD1 in a rat pharmacodynamic model (ED50 = 10 mg/kg).

Benzamide derivatives and uses related thereto

Benzamide derivatives of formula I are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, and n are as defined herein.