96105-72-5 Usage
Uses
Used in Pharmaceutical Research:
3,3,3-Trifluoroalanine hydrochloride is used as a research tool for studying the function and regulation of serine proteases. Its ability to inhibit these enzymes makes it valuable in understanding their role in various biological processes and diseases.
Used in Drug Development:
In the pharmaceutical industry, 3,3,3-trifluoroalanine hydrochloride is used as a potential candidate for the development of new therapeutic drugs. Its inhibitory action on serine proteases suggests its potential in treating conditions where these enzymes are implicated, offering a novel approach to managing related diseases and disorders.
Used in Enzyme Inhibition Studies:
3,3,3-Trifluoroalanine hydrochloride is employed as an inhibitor in enzyme studies to explore the mechanisms of serine protease activity. This helps in identifying the structural and functional aspects of these enzymes, which is essential for the design of more effective and targeted drugs.
Used in Biochemical Assays:
3,3,3-TRIFLUOROALANINE HYDROCHLORIDE is utilized in biochemical assays to measure the activity of serine proteases. By using 3,3,3-trifluoroalanine hydrochloride as a substrate or inhibitor, researchers can assess the effectiveness of these enzymes and their interactions with other molecules in a controlled environment.
Check Digit Verification of cas no
The CAS Registry Mumber 96105-72-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,1,0 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 96105-72:
(7*9)+(6*6)+(5*1)+(4*0)+(3*5)+(2*7)+(1*2)=135
135 % 10 = 5
So 96105-72-5 is a valid CAS Registry Number.
InChI:InChI=1/C3H4F3NO2.ClH/c4-3(5,6)1(7)2(8)9;/h1H,7H2,(H,8,9);1H
96105-72-5Relevant academic research and scientific papers
Biomimetic transamination of α-keto perfluorocarboxylic esters. An efficient preparative synthesis of β,β,β-trifluoroalanine
Soloshonok, Vadim A.,Kukhar, Valery P.
, p. 8307 - 8314 (2007/10/03)
An efficient large-scale preparative synthesis of biologically interesting β,β,β-trifluoroalanine through the biomimetic transamination of the ethyl trifluoropyruvate has been developed. The azomethine-azomethine isomerization of the N-(1-phenyl)ethylimine of ethyl trifluoropyruvate to the N-(l-phenyl)ethylidene alanine ethyl ester, a key stage of the process, was found to occur under the mild reaction conditions, in a triethylamine solution at rt. The proposed working mechanistic rationale accounting for the easiness of the isomerization and its stereochemical outcome, involves unusual non-asymmetric [1,5]-proton shift transfer from the methine carbon to the enolate oxygen.
New Synthetic Pathways to 3,3,3-Trifluoroalanine, 2-Deutero-3,3,3-trifluoroalanine and their Derivatives
Burger, Klaus,Hoess, Eva,Gaa, Karl,Sewald, Norbert,Schierlinger, Christian
, p. 361 - 384 (2007/10/02)
New synthetic pathways to 3,3,3-trifluoroalanine, 2-deutero-3,3,3-trifluoroalanine, their esters, amides, and thioamides are described, starting from hexafluoroacetone, and trifluoropyruvates, respectively.
