96105-72-5 Usage
General Description
3,3,3-Trifluoroalanine hydrochloride is a synthetic compound that consists of an alanine molecule with three fluorine atoms attached to its carbon backbone. The hydrochloride salt form of this chemical is often used in pharmaceutical research and drug development. It is known to be a potent inhibitor of serine proteases, which are enzymes involved in various biological processes, including blood clotting and digestion. This makes 3,3,3-trifluoroalanine hydrochloride a valuable tool for studying the function and regulation of serine proteases, as well as a potential candidate for the development of new therapeutic drugs targeting these enzymes.
Check Digit Verification of cas no
The CAS Registry Mumber 96105-72-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,1,0 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 96105-72:
(7*9)+(6*6)+(5*1)+(4*0)+(3*5)+(2*7)+(1*2)=135
135 % 10 = 5
So 96105-72-5 is a valid CAS Registry Number.
InChI:InChI=1/C3H4F3NO2.ClH/c4-3(5,6)1(7)2(8)9;/h1H,7H2,(H,8,9);1H
96105-72-5Relevant articles and documents
Biomimetic transamination of α-keto perfluorocarboxylic esters. An efficient preparative synthesis of β,β,β-trifluoroalanine
Soloshonok, Vadim A.,Kukhar, Valery P.
, p. 8307 - 8314 (2007/10/03)
An efficient large-scale preparative synthesis of biologically interesting β,β,β-trifluoroalanine through the biomimetic transamination of the ethyl trifluoropyruvate has been developed. The azomethine-azomethine isomerization of the N-(1-phenyl)ethylimine of ethyl trifluoropyruvate to the N-(l-phenyl)ethylidene alanine ethyl ester, a key stage of the process, was found to occur under the mild reaction conditions, in a triethylamine solution at rt. The proposed working mechanistic rationale accounting for the easiness of the isomerization and its stereochemical outcome, involves unusual non-asymmetric [1,5]-proton shift transfer from the methine carbon to the enolate oxygen.
