96110-83-7Relevant academic research and scientific papers
Ortho-mono-substituted amino)phenylimines
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, (2008/06/13)
Novel ortho-(mono-substituted amino)phenylimines being intermediates to psychotropic drugs and other drugs are economically and industrially prepared by reacting anilines with nitriles in the presence of a boron trifluoride ether adduct and a halide-type
Process for preparing 1-substituted-1,4-benzodiazepine derivatives
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, (2008/06/13)
Improvement in the production of psychotropic 1-substituted-1,3-dihydro-1,4-benzodiazepin-2-ones starting from 2-(1-substituted)amino-benzophenonimines through novel intermediates of the formula: STR1 (wherein R is hydrogen, methyl or benzyl, R1/sup
Aminohaloborane in Organic Synthesis. IX. Exclusive ortho Acylation Reaction of N-Monoaminoalkylanilines
Adachi, Makoto,Sasakura, Kazuyuki,Sugasawa, Tsutomu
, p. 1826 - 1835 (2007/10/02)
The exclusive ortho acylation reaction of aniline derivatives using boron trichloride made possible the one-step synthesis of 2-acyl-N-monoaminoalkylanilines (1) and the corresponding imines (2) from N-monoaminoalkylanilines, even in the case of compounds with a bulky substituent at the nitrogen atom.Conventional methods only give 1 via elaborate procedures.Keywords: regioselective reaction; 2-acylaniline derivative; 2-acylaniline-imine derivative; boron trichloride
