96121-14-1

Upstream product

• 14527-26-5 2-methylisothiourea sulphate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Downstream Products

• 55323-83-6 6-phenyl-2H-3,4-dihydro-1,3-oxazine-2,4-dione 
• 100008-30-8 2-(methylamino)-6-phenyl-4(3H)-pyrimidinone 
• 1279017-51-4 2-methylamino-4-iodo-6-phenylpyrimidine 
• 24371-54-8 1,6-diphenyluracil 
• 42542-57-4 1-methyl-6-phenyl-2,4(1H,3H)-pyrimidinedione 

Relevant academic research and scientific papers

6-Aryluracils

This invention relates to the use of 6-aryluracils as antiinflammatory and antiarthritic agents and also to both novel intermediates and novel processes for the preparation of selected 6-aryluracils.

REGIOSPECIFIC SYNTHESIS OF N-1 AND N-2 SUBSTITUTED PYRIMIDONES EMPLOYING A NOVEL 1,3-OXAZINE PREPARATION

Reaction of ethyl benzoylacetate with methylthiopseudourea resulted in expulsion of methylmercaptan to afford 2-amino-6-phenyl-4H-1,3-oxazin-4-one in good yield.This novel oxazine synthesis was exploited to secure N-1 and N-2 substituted pyrimidinones regiospecifically.