96136-31-1Relevant academic research and scientific papers
CYCLOPROPANES AS CONFORMATIONALLY RESTRICTED PEPTIDE ISOSTERES. DESIGN AND SYNTHESIS OF NOVEL COLLAGENASE INHIBITORS
Martin, Stephen F.,Oalmann, Christopher J.,Liras, Spiros
, p. 3521 - 3532 (1993)
The 1,2,3-trisubstituted cyclopropane derivatives 9 and 10 were prepared as conformationally constrained analogues of the known collagenase inhibitor 8.The syntheses of 9 and 10 featured the highly enantioselective Rh24 catalyzed cyclization of th
