96144-03-5Relevant academic research and scientific papers
CHEMISTRY OF DIAZO DICARBONYL COMPOUNDS. X. SYNTHESIS, STEREOCHEMISTRY, AND WOLFF REARRANGMENT OF cis- AND trans-4,6-DI-TERT-BUTYL-2-DIAZOCYCLOHEXANE-1,3-DIONES
Nikolaev, V. A.,Korneev, S. M.,Terent'eva, I. V.,Korobistyna, I. K.
, p. 1845 - 1858 (2007/10/02)
Stereoisomeric cis- and trans-4,6-di-tert-butyl-2-diazocyclohexane-1,3-diones and their deuterated analogs (d2-4,6) were synthesized, a method for separating the stereoisomers was developed, and their configurations were established.The photoch
An improved synthesis of 2-diazo-1,3-diketones
Popic,Korneev,Nikolaev,Korobitsyna
, p. 195 - 198 (2007/10/02)
The sodium hydride/dibenzo-18-crown-6 ether system was found to be an effective base for the synthesis of 1,3-diketones by the Claisen condensation. The use of potassium fluoride (with or without crown ether) as the base in diazo-transfer reactions extends this reaction to the synthesis of hindered diazo diketones. In the case of isomeric 1,3-diketones, the stereoselectivity of the process considerably rises.
