96172-86-0Relevant academic research and scientific papers
Synthesis and biological evaluation of novel symmetry bis-enediynes
Tseng, Kuo-Feng,Lin, Chi-Fong,Lo, Yu-Hsiang,Hu, Yi-Ling,Chen, Li-Yi,Yang, Sheng-Huei,Lin, Shinne-Ren,Chang, Long-Sen,Wu, Ming-Jung
experimental part, p. 35 - 41 (2009/04/07)
A series of acyclic symmetry bis-enediynes have been synthesized successfully and their bioactivities were evaluated. Among them, 1,6-bis(4-((2-(pyridin-2-ylethynyl)phenyl)ethynyl)phenoxy)hexane 8g showed good inhibition activity against the CCRF-CEM (GI
Synthesis of Acetylene-Terminated α,ω-Bisphenoxyalkanes
Babirad, Stephan A.,Feld, William A.
, p. 140 - 141 (2007/10/02)
Nine, α,ω-bis(4-ethynylphenoxy)alkanes were synthesized from the corresponding α,ω-dibromoalkanes by (1) reaction with p-bromophenol/KOH, (2) palladium-catalyzed coupling with 2-methyl-3-butyn-2-ol, and (3) caustic hydrolysis of the hydroxy intermediates.The structures of the ethynyl compounds were confirmed by IR, (1)H NMR, and DSC.
