96177-47-8Relevant academic research and scientific papers
Cross metathesis of β-carotene with electron-deficient dienes. A direct route to retinoids
Wojtkielewicz, Agnieszka,Maj, Jadwiga,Morzycki, Jacek W.
supporting information; experimental part, p. 4734 - 4737 (2011/03/18)
Cross metathesis (CM) reactions of β-carotene and alkenes occur regioselectively in the presence of the Hoveyda second generation catalyst. Scission of the C15-C15′ and C11-C12 bonds of β-carotene in all CM reactions predominates. The reaction with ethyl
Synthesis and Antitumor Activity of Retinoids with Modified Polar Head. Communication I
Deryabina, E. L.,Khodonov, A. A.,Cherevataya, G. V.,Kirillova, Yu. G.,Shvets, V. I.,et al.
, p. 811 - 818 (2007/10/03)
Several retinoids with a modified polar group were synthesized.Biological screening using HL-60 promyelocyte leukemia cells showed that the free carboxyl in the retinoid molecules is not the only group responsible for exhibiting the differentiating activi
