96201-10-4Relevant articles and documents
A Tunable and Enantioselective Hetero-Diels–Alder Reaction Provides Access to Distinct Piperidinoyl Spirooxindoles
Jayakumar, Samydurai,Louven, Kathrin,Strohmann, Carsten,Kumar, Kamal
supporting information, p. 15945 - 15949 (2017/11/27)
The active complexes of chiral N,N′-dioxide ligands with dysprosium and magnesium salts catalyze the hetero-Diels–Alder reaction between 2-aza-3-silyloxy-butadienes and alkylidene oxindoles to selectively form 3,3′- and 3,4′-piperidinoyl spirooxindoles, respectively, in very high yields and with excellent enantioselectivities. The exo-selective asymmetric cycloaddition successfully regaled the construction of sp3-rich and highly substituted natural-product-based spirooxindoles supporting many chiral centers, including contiguous all-carbon quaternary centers.
The Utility of t-Butyldimethylsilane as an Effective Silylation Reagent for the Protection of Functional Groups
Yamamoto, Keiji,Takemae, Makoto
, p. 2111 - 2113 (2007/10/02)
Treatment of compounds containing functional groups, such as alcohols, amines, and carboxylic acids, with t-butyldimethylsilane in the presence of a catalytic amount of palladium on carbon is described to provide a new, convenient method for the introduction of a t-butyldimethylsilyl (TBDMS) group.
1,8-DIAZABICYCLOUNDEC-7-ENE(DBU): AN EFFECTIVE BASE FOR THE INTRODUCTION OF t-BUTYLDIMETHYLSILYL GROUP IN ORGANIC COMPOUNDS.
Aizpurua, Jesus M.,Palomo, Claudio
, p. 475 - 476 (2007/10/02)
Reaction of alcohols, thiols, amines, carboxylic acids, phenols, hydroquinones, ketoesters and amides with equimolecular amounts of t-butyldimethylchlorosilane and DBU, even in solvents other than dimethylformamide affords the corresponding t-butyldimethy
