96219-87-3

Usage

Uses

Used in Pharmaceutical Industry:
(3-Aminopyrazol-4-yl)(2-thienyl)methanone is used as a phosphodiesterase 5 inhibitor for the development of drugs targeting various medical conditions. Its role in inhibiting phosphodiesterase 5 can lead to increased levels of cyclic guanosine monophosphate (cGMP), which is involved in the regulation of smooth muscle relaxation and blood flow. This property makes it a promising candidate for the treatment of conditions such as erectile dysfunction, pulmonary arterial hypertension, and other cardiovascular diseases.
Used in Chemical Research:
(3-Aminopyrazol-4-yl)(2-thienyl)methanone is used as a research compound in the field of organic chemistry. Its unique structural characteristics, including the presence of a pyrazole ring, make it a valuable subject for studying the reactivity and properties of heterocyclic compounds. Researchers can use (3-AMINOPYRAZOL-4-YL)(2-THIENYL)METHANONE to explore new synthetic routes, reaction mechanisms, and potential applications in various chemical processes.
Used in Material Science:
(3-Aminopyrazol-4-yl)(2-thienyl)methanone can be used as a building block or intermediate in the synthesis of various materials with specific properties. Its structural features, such as the presence of a pyrazole ring and a thienyl group, can contribute to the development of new materials with potential applications in areas such as electronics, sensors, and energy storage.

Upstream product

• 10308-82-4 aminoguanidine nitrate 
• 34772-98-0 (2E)-3-(dimethylamino)-1-thien-2-ylprop-2-en-1-one 
• 88-15-3 2-Acetylthiophene 

Downstream Products

• 850786-63-9 [7-(3-nitrophenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-2-thienyl-methanone 
• 931114-22-6 [7-(4-nitro-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-thiophen-2-yl-methanone 
• 1019209-61-0 C₂₃H₂₁FN₄O₂S 
• 1019209-62-1 C₂₄H₂₃FN₄O₂S 
• 1019209-69-8 N-(3-hydroxy-propyl)-N-{3-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-phenyl}-acetamide 
• 1019209-70-1 N-(4-hydroxy-butyl)-N-{3-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-phenyl}-acetamide 
• 1019209-85-8 4-nitro-N-methyl-N-{3-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-phenyl}-benzamide 
• 1001083-37-9 [2H]-Indiplon 
• 325715-02-4 N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-a]-pyrimidin-7-yl}phenyl)acetamide 
• 1147866-56-5 [7-(4-methoxy-3-nitrophenyl)pyrazolo[1,5-a]pyrimidin-3-yl](thien-2-yl)methanone 
• 879373-78-1 [7-(4-fluoro-3-nitrophenyl)pyrazolo[1,5-a]pyrimidin-3-yl](thien-2-yl)methanone 
• 879371-74-1 [7-(2-chloro-5-nitrophenyl)pyrazolo[1,5-a]pyrimidin-3-yl](thien-2-yl)methanone 
• 1147866-57-6 [7-(4-chloro-3-nitrophenyl)pyrazolo[1,5-a]pyrimidin-3-yl](thien-2-yl)methanone 
• 1147866-55-4 [7-(4-methyl-3-nitrophenyl)pyrazolo[1,5-a]pyrimidin-3-yl](thien-2-yl)methanone 

Relevant academic research and scientific papers

Salts And Co-Crystals of Pyrazolopyrimidine Compounds, Compositions Thereof And Methods For Their Production And Use

The invention provides pharmaceutically acceptable salts and co-crystals of pyrazolopyrimidine compounds such as zaleplon, indiplon and ocinaplon, processes for their preparation, compositions comprising such salts and co-crystals and methods of using such salts and co-crystals for treating various diseases and conditions.

NOVEL HETEROBICYCLIC COMPOUNDS

This invention relates to novel pyrazolo-pyrimidine compounds and their use as analytical tools and in methods of treating neurological disorders, including sleep disorders such as insomnia.

Pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as novel antiproliferative agents: Exploration of core and headpiece structure-activity relationships

A novel series of antiproliferative agents containing pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides, selective for p21-deficient cells, were identified by high-throughput screening. Exploration of the SAR relationships in the headpiece, core, and tailpiece

Method of using substituted pyrazolo [1,5-a] pyrimidines

This invention relates to novel methods of use of certain pyrazolo[1,5-a]pyrimidine compounds and the therapeutically acceptable salts thereof. This invention also relates to novel methods of using these compounds as anti-proliferative agents in mammals, including humans.

Substituted pyrazolo[1,5-a] pyrimidines and process for making same

This invention relates to novel pyrazolo[1,5-a]pyrimidine compounds and the therapeutically acceptable salts thereof. These compounds are useful as anti-proliferative agents in mammals, including humans.

Pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as novel anti-proliferative agents: Parallel synthesis for lead optimization of amide region

A novel series of p21 chemoselective agents containing a pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides were identified by high throughput screening. Optimization of the amide region by parallel synthesis and the iterative design toward understanding structu

N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto

N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide, and use of the same as a sedative-hypnotic, anxiolytic, anticonvulsant, and skeletal muscle relaxant agent. Compositions containing N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide, as well as pharmaceutically acceptable salts thereof, are also disclosed.