850786-63-9

Upstream product

• 96219-87-3 (3-amino-1H-pyrazol-4-yl)(thien-2-yl)methanone 
• 115955-48-1 3-(dimethylamino)-1-(3-nitrophenyl)-2-propen-1-one 
• 121-89-1 3-Nitroacetophenone 
• 96219-87-3 (5-amino-1H-pyrazol-4-yl)-thiophen-2-yl-methanone 
• 1163721-90-1 (Z)-3-Dimethylamino-1-(3-nitro-phenyl)-propenone 

Downstream Products

• 850786-65-1 N-[3-[3-(thien-2-ylcarbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]cyclopropanecarboxamide 
• 850786-64-0 [7-(3-aminophenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-thien-2-yl-methanone 

Relevant academic research and scientific papers

Method of using substituted pyrazolo [1,5-a] pyrimidines

This invention relates to novel methods of use of certain pyrazolo[1,5-a]pyrimidine compounds and the therapeutically acceptable salts thereof. This invention also relates to novel methods of using these compounds as anti-proliferative agents in mammals, including humans.

Substituted pyrazolo[1,5-a] pyrimidines and process for making same

This invention relates to novel pyrazolo[1,5-a]pyrimidine compounds and the therapeutically acceptable salts thereof. These compounds are useful as anti-proliferative agents in mammals, including humans.

Pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as novel anti-proliferative agents: Parallel synthesis for lead optimization of amide region

A novel series of p21 chemoselective agents containing a pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides were identified by high throughput screening. Optimization of the amide region by parallel synthesis and the iterative design toward understanding structu