96220-13-2 Usage
General Description
3-(3-furyl)-3-oxopropanenitrile, also known as furfuryl 3-oxopropanenitrile, is a chemical compound with the molecular formula C7H5NO2. It is a nitrile derivative of furfural, a natural compound found in many plants and used in the production of various chemicals. The compound is often used as a building block in organic synthesis, particularly in the manufacture of pharmaceuticals and agrochemicals. It has a distinct furan odor and is considered to be a potential irritant to the skin, eyes, and respiratory system. Furfuryl 3-oxopropanenitrile is also a known carcinogen and mutagen, and as such, proper handling and safety precautions are necessary when working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 96220-13-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,2,2 and 0 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 96220-13:
(7*9)+(6*6)+(5*2)+(4*2)+(3*0)+(2*1)+(1*3)=122
122 % 10 = 2
So 96220-13-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H5NO2/c8-3-1-7(9)6-2-4-10-5-6/h2,4-5H,1H2
96220-13-2Relevant articles and documents
A Pd-catalyzed asymmetric allylic substitution cascade: Via an asymmetric desymmetrization for the synthesis of bicyclic dihydrofurans
Xu, Kai,Liu, Hao,Hou, Yilin,Shen, Jiefeng,Liu, Delong,Zhang, Wanbin
, p. 13295 - 13298 (2019)
A Pd-catalyzed asymmetric allylic substitution cascade of allylic meso-dicarbonates with 3-oxo-nitriles has been developed for the synthesis of chiral bicyclic dihydrofurans bearing two vicinal carbon stereocenters. The reaction proceeds via an asymmetric desymmetrization process with the desired products being obtained in high yields and with up to 97% ee. The reaction was performed on a gram-scale and the corresponding bicyclic dihydrofurans could undergo several transformations. The methodology provides an efficient synthetic route to biologically active chiral bicyclic dihydrofurans derivatives.
