96240-04-9Relevant academic research and scientific papers
One-pot synthesis of 1,4-diamines from allyl halides and amines via a rhodium-catalysed multistep reaction sequence under hydroformylation conditions
Rische, Thorsten,Eilbracht, Peter
, p. 3917 - 3922 (1999)
1,4-Diamines 8 are prepared with good yields and selectivities by the reaction of methallyl chloride (6), secondary amines 7, carbon monoxide and hydrogen in presence of [Rh(cod)Cl]2 as catalyst via a one-pot nucleophilic substitution hydroform
Indirect Electroreductive Cyclisation of N-Allylic and N-Propargylbromo Amides and o-Bromoacryloylanilides using Nickel(II) Complexes as Electron-transfer Catalysts
Ozaki, Shigeko,Matsushita, Hidenori,Ohmori, Hidenobu
, p. 2339 - 2344 (2007/10/02)
Nickel(II) complex-catalysed indirect electroreduction of N-allylic and N-propargyl-α-bromo amides and o-bromoacryloylanilides gave the corresponding 5-membered lactams.The product distribution was affected by the ability of the solvent to donate hydrogen atom.The electroreduction of N-allyl-N-(bromoacetyl)toluene-p-sulfonamide 1a in DMF and acetonitrile yielded as main product the 4-methylpyrrolidinone 2a (41percent) and the 4-(bromomethyl)pyrrolidinone 3a (33percent), respectively.On addition of 2 mol equiv. of a hydrogen-atom donor (Ph2PH) to the reaction of bromo amide 1a in acetonitrile, compound 1a provided compound 2a (58percent) as the sole cylised product.
Synthesis of Pyrrolidines and Pyrrolidinones by the Rhodium Complex Catalyzed Cyclization of Unsaturated Amines
Zhou, Jian-Qiang,Alper, Howard
, p. 3328 - 3331 (2007/10/02)
N-Allylic arylamines react with carbon monoxide, sodium borohydride, 2-propanol, and catalytic amounts of the zwitterionic complex η6-C6H6BPh3-Rh(COD)+ (1), to form pyrrolidines as the main products in most cases.Pyrrolidinones result from N-allylic alkylamines.An alternate route to the lactams from N-allylic alkylamines involves synthesis gas instead of CO/NaBH4, together with the dual catalytic system 1/2.Complementary to the N-allylic arylamine route to pyrrolidines with NaBH4 and 1 is the use of synthesis gas, 1, and 1,4-bis(diphenylphosphino)butane.
The Synthesis of 4-Methyl-2-pyrrolidones and 3-Methyl-1-pyrrolidines and Their Mass Spectral Study
Lin, Tay-yean,Kingsbury, Charles A.,Cromwell, Norman H.
, p. 1871 - 1875 (2007/10/02)
A number of 1-alkyl-4-methyl-2-pyrrolidones have been prepared from methyl 4-alkylamino-3-methyl butenoates.The corresponding 1-alkyl-3-methyl-pyrrolidines are obtainable by the reduction of the pyrrolidones with lithium aluminium hydride.The mass spectra
