One-pot synthesis of 1,4-diamines from allyl halides and amines via a rhodium-catalysed multistep reaction sequence under hydroformylation conditions

Article abstract of DOI:10.1016/S0040-4020(99)00111-8

1,4-Diamines 8 are prepared with good yields and selectivities by the reaction of methallyl chloride (6), secondary amines 7, carbon monoxide and hydrogen in presence of [Rh(cod)Cl]₂ as catalyst via a one-pot nucleophilic substitution hydroform