96253-11-1

Upstream product

• 58-96-8 uridine 
• 96253-10-0 1-[2,3-epoxy-5-O-(triphenylmethyl)-β-D-lyxofuranosyl]pyrimidine-2,4(1H,3H)-dione 
• 70277-75-7 lithium acetylide 

Downstream Products

• 174074-45-4 1-<2-O-acetyl-3-deoxy-3-α-ethynyl-5-O-(triphenylmethyl)-β-D-arabinofuranosyl>pyrimidine-2,4(1H,3H)-dione 
• 174074-46-5 1-<3-deoxy-3-α-ethynyl-2-O--5-O-(triphenylmethyl)-β-D-arabinofuranosyl>pyrimidine-2,4(1H,3H)-dione 
• 174074-51-2 1-<2,3-dideoxy-3-ethynyl-5-O-(triphenylmethyl)-β-D-ribofuranosyl>pyrimidine-2,4(1H,3H)-dione 

Relevant academic research and scientific papers

3',4'-diethynyl-2',3',5'-trideoxy-5'-noruridine: A new self-polymerizable 2'-deoxyribonucleoside analogue

In 10 steps, 3',4'-diethynyl-2',3',5'-trideoxy-5'-noruridine (14) was synthesized in 5% overall yield from commercial uridine, using conventional methods of nucleoside chemistry. As two functional groups capable to react with each other are present in the

NOVEL NUCLEOSIDE ANALOGUES VIA DIRECT ATTACK OF CARBON NUCLEOPHILES ON NUCLEOSIDES CONTAINING EPOXY-SUGARS

Direct ring-opening of the epoxyde ring in 1-(5'-O-tityl-2',3'-anhydro-β-D-lyxofuranosyl) uracil(1) by lithium acetylide or vinylmagnesium bromide/cuprous iodide affords the corresponding 5'-O-trityl-3'-C-substituted-3'-deoxy-ara-uridine species.