96286-46-3Relevant academic research and scientific papers
SYNTHESIS OF NEW 5-NITROTETRAHYDRO-1,3-0XAZINE DERIVATIVES VIA ELECTRON-TRANSFER REACTIONS
Crozet, Michel P.,Vanelle, Patrice
, p. 5477 - 5484 (2007/10/02)
5-Nitrotetrahydro-1,3-oxazine salts are found to be useful nucleophiles for SRN1 reactions with p-nitrobenzyl chloride, 2,2-dinitropropane and 1-methyl-2-chloromethyl-5-nitroimidazole.From C-alkylation products, base promoted nitrous acid elimination and electron-transfer elimination of the two nitro groups afford new tetrahydro-1,3-oxazines with respectively a tri- and tetrasubstituted double bond at the 5 position.These new tetrahydro-1,3-oxazines can be hydrolysed to the corresponding ethylenic aminoalcohols by heating with hydrochloric acid.
REACTIONS SRN1 EN SERIE HETEROCYCLIQUE: I - REACTIVITE DE SELS DE NITRO-5 TETRAHYDROOXAZINES-1,3
Crozet, Michel P.,Vanelle, Patrice
, p. 323 - 326 (2007/10/02)
Heterocyclic nitronate anions prepared from 3-ethyl-5-hydroxymethyl-5-nitrotetrahydro-1,3-oxazine are found to be suitable nucleophiles for SRN1 reactions.Base-promoted nitrous acid elimination from C-alkylation product gives rise to new tetrah
